Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot

Chun An Chen, Ssu Yuan Chen, Jou Kou Wang, Wen Yih Isaac Tseng, Hsin Hui Chiu, Chung I. Chang, Ing Sh Chiu, Yih Sharng Chen, Ming Chun Yang, Chun Wei Lu, Ming Tai Lin, Mei Hwan Wu

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10 Citations (Scopus)

Abstract

Background Right ventricular (RV) outflow tract obstruction (RVOTO) might protect the RV from adverse remodeling caused by significant pulmonary regurgitation (PR) in patients with repaired tetralogy of Fallot (rTOF), but the underlying mechanisms and influences on exercise tolerance remain unclear. This study sought to investigate the impacts from mild RVOTO on ventricular remodeling and exercise capacity in rTOF. Methods Eighty-five rTOF patients with a PR fraction ≥20% were assessed with cardiac magnetic resonance, cardiopulmonary exercise test, and echocardiography. Patients with a peak RVOT pressure gradient 20-50 mmHg were considered to have mild RVOTO (n = 29), while those with a gradient

Original languageEnglish
Pages (from-to)555-561
Number of pages7
JournalAmerican Heart Journal
Volume167
Issue number4
DOIs
Publication statusPublished - Apr 2014

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Pulmonary Valve Insufficiency
Ventricular Outflow Obstruction
Tetralogy of Fallot
Ventricular Remodeling
Exercise Tolerance
Exercise Test
Echocardiography
Magnetic Resonance Spectroscopy
Exercise
Pressure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot. / Chen, Chun An; Chen, Ssu Yuan; Wang, Jou Kou; Tseng, Wen Yih Isaac; Chiu, Hsin Hui; Chang, Chung I.; Chiu, Ing Sh; Chen, Yih Sharng; Yang, Ming Chun; Lu, Chun Wei; Lin, Ming Tai; Wu, Mei Hwan.

In: American Heart Journal, Vol. 167, No. 4, 04.2014, p. 555-561.

Research output: Contribution to journalArticle

Chen, Chun An ; Chen, Ssu Yuan ; Wang, Jou Kou ; Tseng, Wen Yih Isaac ; Chiu, Hsin Hui ; Chang, Chung I. ; Chiu, Ing Sh ; Chen, Yih Sharng ; Yang, Ming Chun ; Lu, Chun Wei ; Lin, Ming Tai ; Wu, Mei Hwan. / Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot. In: American Heart Journal. 2014 ; Vol. 167, No. 4. pp. 555-561.
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AU - Tseng, Wen Yih Isaac

AU - Chiu, Hsin Hui

AU - Chang, Chung I.

AU - Chiu, Ing Sh

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AU - Lu, Chun Wei

AU - Lin, Ming Tai

AU - Wu, Mei Hwan

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