Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot

Chun An Chen; Ssu Yuan Chen; Jou Kou Wang; Wen Yih Isaac Tseng; Hsin Hui Chiu; Chung I. Chang; Ing Sh Chiu; Yih Sharng Chen; Ming Chun Yang; Chun Wei Lu; Ming Tai Lin; Mei Hwan Wu

doi:10.1016/j.ahj.2013.12.026

Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot

Chun An Chen, Ssu Yuan Chen, Jou Kou Wang, Wen Yih Isaac Tseng, Hsin Hui Chiu, Chung I. Chang, Ing Sh Chiu, Yih Sharng Chen, Ming Chun Yang, Chun Wei Lu, Ming Tai Lin, Mei Hwan Wu

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Background Right ventricular (RV) outflow tract obstruction (RVOTO) might protect the RV from adverse remodeling caused by significant pulmonary regurgitation (PR) in patients with repaired tetralogy of Fallot (rTOF), but the underlying mechanisms and influences on exercise tolerance remain unclear. This study sought to investigate the impacts from mild RVOTO on ventricular remodeling and exercise capacity in rTOF. Methods Eighty-five rTOF patients with a PR fraction ≥20% were assessed with cardiac magnetic resonance, cardiopulmonary exercise test, and echocardiography. Patients with a peak RVOT pressure gradient 20-50 mmHg were considered to have mild RVOTO (n = 29), while those with a gradient

Original language	English
Pages (from-to)	555-561
Number of pages	7
Journal	American Heart Journal
Volume	167
Issue number	4
DOIs	https://doi.org/10.1016/j.ahj.2013.12.026
Publication status	Published - Apr 2014

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1016/j.ahj.2013.12.026

Cite this

Chen, C. A., Chen, S. Y., Wang, J. K., Tseng, W. Y. I., Chiu, H. H., Chang, C. I., Chiu, I. S., Chen, Y. S., Yang, M. C., Lu, C. W., Lin, M. T., & Wu, M. H. (2014). Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot. American Heart Journal, 167(4), 555-561. https://doi.org/10.1016/j.ahj.2013.12.026

Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot. / Chen, Chun An; Chen, Ssu Yuan; Wang, Jou Kou et al.

In: American Heart Journal, Vol. 167, No. 4, 04.2014, p. 555-561.

Research output: Contribution to journal › Article › peer-review

Chen, CA, Chen, SY, Wang, JK, Tseng, WYI, Chiu, HH, Chang, CI, Chiu, IS, Chen, YS, Yang, MC, Lu, CW, Lin, MT & Wu, MH 2014, 'Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot', American Heart Journal, vol. 167, no. 4, pp. 555-561. https://doi.org/10.1016/j.ahj.2013.12.026

@article{b72990eea371413997226c7346bbd0f8,

title = "Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot",

abstract = "Background Right ventricular (RV) outflow tract obstruction (RVOTO) might protect the RV from adverse remodeling caused by significant pulmonary regurgitation (PR) in patients with repaired tetralogy of Fallot (rTOF), but the underlying mechanisms and influences on exercise tolerance remain unclear. This study sought to investigate the impacts from mild RVOTO on ventricular remodeling and exercise capacity in rTOF. Methods Eighty-five rTOF patients with a PR fraction ≥20% were assessed with cardiac magnetic resonance, cardiopulmonary exercise test, and echocardiography. Patients with a peak RVOT pressure gradient 20-50 mmHg were considered to have mild RVOTO (n = 29), while those with a gradient ",

author = "Chen, {Chun An} and Chen, {Ssu Yuan} and Wang, {Jou Kou} and Tseng, {Wen Yih Isaac} and Chiu, {Hsin Hui} and Chang, {Chung I.} and Chiu, {Ing Sh} and Chen, {Yih Sharng} and Yang, {Ming Chun} and Lu, {Chun Wei} and Lin, {Ming Tai} and Wu, {Mei Hwan}",

year = "2014",

month = apr,

doi = "10.1016/j.ahj.2013.12.026",

language = "English",

volume = "167",

pages = "555--561",

journal = "American Heart Journal",

issn = "0002-8703",

publisher = "Mosby Inc.",

number = "4",

}

TY - JOUR

T1 - Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot

AU - Chen, Chun An

AU - Chen, Ssu Yuan

AU - Wang, Jou Kou

AU - Tseng, Wen Yih Isaac

AU - Chiu, Hsin Hui

AU - Chang, Chung I.

AU - Chiu, Ing Sh

AU - Chen, Yih Sharng

AU - Yang, Ming Chun

AU - Lu, Chun Wei

AU - Lin, Ming Tai

AU - Wu, Mei Hwan

PY - 2014/4

Y1 - 2014/4

N2 - Background Right ventricular (RV) outflow tract obstruction (RVOTO) might protect the RV from adverse remodeling caused by significant pulmonary regurgitation (PR) in patients with repaired tetralogy of Fallot (rTOF), but the underlying mechanisms and influences on exercise tolerance remain unclear. This study sought to investigate the impacts from mild RVOTO on ventricular remodeling and exercise capacity in rTOF. Methods Eighty-five rTOF patients with a PR fraction ≥20% were assessed with cardiac magnetic resonance, cardiopulmonary exercise test, and echocardiography. Patients with a peak RVOT pressure gradient 20-50 mmHg were considered to have mild RVOTO (n = 29), while those with a gradient

AB - Background Right ventricular (RV) outflow tract obstruction (RVOTO) might protect the RV from adverse remodeling caused by significant pulmonary regurgitation (PR) in patients with repaired tetralogy of Fallot (rTOF), but the underlying mechanisms and influences on exercise tolerance remain unclear. This study sought to investigate the impacts from mild RVOTO on ventricular remodeling and exercise capacity in rTOF. Methods Eighty-five rTOF patients with a PR fraction ≥20% were assessed with cardiac magnetic resonance, cardiopulmonary exercise test, and echocardiography. Patients with a peak RVOT pressure gradient 20-50 mmHg were considered to have mild RVOTO (n = 29), while those with a gradient

UR - http://www.scopus.com/inward/record.url?scp=84897824694&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897824694&partnerID=8YFLogxK

U2 - 10.1016/j.ahj.2013.12.026

DO - 10.1016/j.ahj.2013.12.026

M3 - Article

C2 - 24655705

AN - SCOPUS:84897824694

SN - 0002-8703

VL - 167

SP - 555

EP - 561

JO - American Heart Journal

JF - American Heart Journal

IS - 4

ER -

Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this