機械通氣導致肺損傷

Translated title of the contribution: Ventilator Induced Lung Injury

林 蕙鈴(Hui-Ling Lin), Ling-Ling Chiang, 施 崇鴻(Chung-Hung Shih), 楊 式興(Shih-Hsing Yang), Chien-Ling Su

Research output: Contribution to journalArticle

Abstract

Mechanical ventilation has been used in critical care for decades to save patients' lives in critical settings, but it has potential complications, such as ventilator-induced lung injury (VILI). Barotrauma is widely referred to as the VILI, but, with advanced microscopic technology, researchers have found that lung injury might also be the consequence of inflammatory response to mechanical ventilation. During normal gas exchange, alveoli structure is maintained by surface tension and connective tissues; however, when the lungs are injured, the surface tension loses its function of maintaining the alveolar structure. For instance, the repeating recruitment and derecruitment of the lungs creates inflammatory responses. The mechanisms causing acute lung injury during mechanical ventilation include volutrauma, atelectrauma, biotrauma, barotrauma, and oxygen toxicity. Understanding the mechanisms of VILI facilitates the prevention of worsening disease.
Translated title of the contributionVentilator Induced Lung Injury
Original languageTraditional Chinese
Pages (from-to)131-138
Number of pages8
Journal呼吸治療
Volume7
Issue number1
DOIs
Publication statusPublished - 2008

Keywords

  • VILI
  • barotraumas
  • mechanical ventilator
  • lung injury

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