Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome in adults prognostic factors for outcomes

Meng Yu Wu, Chung Chi Huang, Tzu I. Wu, Chin Liang Wang, Pyng Jing Lin

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Despite a therapeutic option for severe acute respiratory distress syndrome (ARDS), the survival benefit of venovenous extracorporeal membrane oxygenation (VV-ECMO) is still controversial in adults. This study was aimed at investigating the prognostic factors for ECMO-treated ARDS in adult patients. From 2012 to 2015, 49 patients (median age: 57 years) received VVECMO in our institution and were included in this retrospective study. The indication of VV-ECMO was a severe hypoxemia (PaO2/FiO2 ratio 35cmH2O and a FiO2 >0.8. To decrease the impact of pulmonary injuries associated with the high-pressure ventilation, the settings of MV on VV-ECMO were downgraded accorDing to our protocol. Outcomes of this study were death on VV-ECMO and death in hospital. Important demographic and clinical data during the treatment were collected for outcome analyses. All patients experienced significant improvements in arterial oxygenation onVV-ECMO.Twenty-four hours after initiation ofVV-ECMO, the median PaO2/FiO2 ratio increased from 58 to 172mmHg (P90 hours was the prognostic factor of death before hospital discharge (OR: 7, 95% CI: 1-29, P

Original languageEnglish
Article numbere2870
JournalMedicine (United States)
Volume95
Issue number8
DOIs
Publication statusPublished - Mar 4 2016

ASJC Scopus subject areas

  • Medicine(all)

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