Varicocele Is Associated with Erectile Dysfunction: A Population-Based Case-Control Study

Joseph J. Keller, Yi Kuang Chen, Herng Ching Lin

Research output: Contribution to journalArticle

9 Citations (Scopus)


Introduction. While many studies have been conducted investigating the efficacy of varicocele treatment on fertility, the literature is comparatively sparse concerning the association between varicocele, varicocelectomy, and erectile dysfunction (ED). Aim. This study aimed to estimate the associations between varicocele, varicocelectomy, and ED using a population-based dataset. Methods. This study used data from the Longitudinal Health Insurance Database 2000 in Taiwan. A total of 32,856 cases and 98,568 randomly selected controls were included in this study. Conditional logistic regression analyses were used to examine associations between ED and having been previously diagnosed with varicocele or having underwent a varicocelectomy. Main Outcome Measure. The odds of prior varicocele or having underwent a varicocelectomy between cases and controls. Results. Of the sampled patients, the prevalence of prior varicocele was 3.3% and 1.2% for cases and controls, respectively (P

Original languageEnglish
Pages (from-to)1745-1752
Number of pages8
JournalJournal of Sexual Medicine
Issue number7
Publication statusPublished - Jul 2012


  • Erectile dysfunction
  • Varicocele
  • Varicocelectomy

ASJC Scopus subject areas

  • Urology
  • Obstetrics and Gynaecology
  • Reproductive Medicine

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