Van Der Woude Syndrome: A Case Report

Chang Kai-Ti, Ko Hsuan-Lu, Chang Kai-Ju, Tchaou Wen-Shiun

Research output: Contribution to journalArticle

Abstract

Van der Woude syndrome (VWS) is a rare autosomal dominant clefting syndrome with high penetrance and variable expressions. It is a common cause of syndromic orofacial clefting, accounting for 2% of cleft lip and cleft palate cases. Clinical manifestation includes bilateral lower lip pits, cleft lip, and cleft palate along with hypodontia. It is one of the few syndromes that present a mixture of cleft lip and cleft palate phenotypes in the same family. This case report presents two siblings both affected by VWS with different phenotypes, and facilitates the understanding of the etiology of malformation, epidemiology, clinical manifestations and associated features.
Original languageEnglish
Pages (from-to)46-50
Number of pages5
Journal臺灣兒童牙醫學雜誌
Volume16
Issue number2
DOIs
Publication statusPublished - 2016

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Keywords

  • 唇陷窩
  • 顎裂
  • 唇裂
  • 遺傳性唇顎裂症候群
  • cleft palate
  • cleft lip
  • lip pits
  • Van der Woude syndrome

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