Validation of the EQ-5D in Patients with Traumatic Limb Injury

Mei Chuan Hung, Wen Shian Lu, Sheng Shiung Chen, Wen Hsuan Hou, Ching Lin Hsieh, Jung Der Wang

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Purpose The measurement properties of the EQ-5D have not been explored for patients with traumatic limb injuries. The purpose of this study was to examine the construct validity, predictive validity, and responsiveness of the EQ-5D in patients with traumatic limb injuries. Methods A consecutive cohort of 1,167 patients was assessed with the EQ-5D and the World Health Organization Quality of Life instrument (WHOQOL-BREF) at baseline while the patients were hospitalized because of the injury, and the patients were followed up at 3 months (1,003 patients), 6 months (1,010 patients), and 12 months (987 patients) after injury via telephone interview. Results The utility and visual analogue scale (VAS) scores of the EQ-5D had moderate to high association with the physical and psychological domains and the two general questions (overall QOL and overall health) of the WHOQOL-BREF at all time points except baseline (Pearson’s correlation coefficient >0.3), but the EQ-5D profiles were weakly associated with the social and environment domains of the WHOQOL-BREF (absolute value of Spearman’s correlation coefficient 0.9) at 0–3, 0–6, and 0–12 months after injury. Conclusions The EQ-5D has sufficient construct validity, predictive validity, and responsiveness, and also provides evidence for using the utility of the EQ-5D for cost-utility analyses of patients with traumatic limb injuries in the future.

Original languageEnglish
Article number14
Pages (from-to)387-393
Number of pages7
JournalJournal of Occupational Rehabilitation
Volume25
Issue number2
DOIs
Publication statusPublished - Jun 22 2015

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Extremities
Wounds and Injuries
Social Environment
Visual Analog Scale
Cost-Benefit Analysis
Quality of Life
Interviews
Psychology
Health

Keywords

  • Construct validity
  • EQ-5D
  • Predictive validity
  • Responsiveness
  • Traumatic limb injury

ASJC Scopus subject areas

  • Rehabilitation
  • Occupational Therapy

Cite this

Validation of the EQ-5D in Patients with Traumatic Limb Injury. / Hung, Mei Chuan; Lu, Wen Shian; Chen, Sheng Shiung; Hou, Wen Hsuan; Hsieh, Ching Lin; Wang, Jung Der.

In: Journal of Occupational Rehabilitation, Vol. 25, No. 2, 14, 22.06.2015, p. 387-393.

Research output: Contribution to journalArticle

Hung, Mei Chuan ; Lu, Wen Shian ; Chen, Sheng Shiung ; Hou, Wen Hsuan ; Hsieh, Ching Lin ; Wang, Jung Der. / Validation of the EQ-5D in Patients with Traumatic Limb Injury. In: Journal of Occupational Rehabilitation. 2015 ; Vol. 25, No. 2. pp. 387-393.
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