Uterine sarcoma Part I—Uterine leiomyosarcoma: The Topic Advisory Group systematic review

Kuo Chang Wen, Huann Cheng Horng, Peng Hui Wang, Yi Jen Chen, Ming Shyen Yen, Heung Tat Ng, Yen Hou Chang, Yi Chang, Hsiang Tai Chao, Kuan Chong Chao, Chi Mu Chuang, Chi Hong Ho, Chen Yu Huang, Zhi Chen Hung, Ling Yu Jiang, Hei Yu Lau, Hsin Yang Li, Chi Yao Lin, Chia Hao Liu, Pi Lin SunNae Fang Twu, Hua Hsi Wu, Hann Chin Yu, Fong Yuan Ju, Chih Ping Tsai, Wen Hsun Chang, Yen Mei Hsu, Na Rong Lee, Chih Yao Chen, Ting Chen Chang, Wen Chun Chang, Chii Hou Chen, Ruey Jian Chen, Song Nan Chow, Yih Ron Lien, Bor Ching Sheu, Pao Ling Torng, Men Luh Yen, Wen Ling Lee, Kuan Chin Wang, Chih Long Chang, Chih Ping Chen, Jen Ruei Chen, Tze Chien Chen, Jian Pei Huang, Ming Chao Huang, Yeou Lih Wang, Cheng Chang Chang, Jah Yao Liu, Her Young Su, Yu Chi Wang, Mu Hsien Yu, Lee Wen Huang, Kok Min Seow, Tsung Hsuan Lai, Fa Kung Lee, Ching Hui Chen, Ben Shian Huang, Sheng Mou Hsiao, Hsu Dong Sun, Wen Yih Wu, Sen Wen Teng, Kuo Hu Chen, Jeng Hsiu Hung, Hung Cheng Lai, Chiou Chung Yuan, Ching Hung Hsieh, Chin Jung Wang, Shing Jyh Chang, Man Jung Hung, Shih Tien Hsu, Yu Min Ke, Chien Hsing Lu, Lou Sun, Wei Chun Chang, Yao Ching Hung, Wu Chou Lin, Po Hui Wang, Tze Ho Chen, Yiu Tai Li, Meng Hsing Wu, Kuo Feng Huang, Hung Chun Fu, San Nung Chen, An Jen Chiang, Ju Yueh Li, Li Te Lin, Hsiao Wen Tsai, Kuan Hao Tsui

Research output: Contribution to journalReview article

13 Citations (Scopus)

Abstract

Uterine sarcomas account for 3–7% of all uterine cancers. Because of their rarity, unknown etiology, and highly divergent genetic aberration, there is a lack of consensus on risk factors for occurrence and predictive poor outcomes as well as optimal therapeutic choices. Tumor types according to the World Health Organization classification include leiomyosarcoma, endometrial stroma sarcoma, and undifferentiated sarcoma. Staging is done using the 2014 Federation International Gynecology and Obstetrics and 2010 American Joint Committee on Cancer tumor, lymph node, and metastases systems. Tumor grade can be classified based on the French Federation of Cancer Centers Sarcoma Group system or the Broder's system that incorporates tumor differentiation, mitotic count, and tumor necrosis. This review is a series of articles discussing uterine sarcoma, and this is Part I, which focuses on one of the subtypes of uterine sarcomas—uterine leiomyosarcoma. The clinical characteristics, diagnosis, outcome, and recent advances are summarized in this article.

Original languageEnglish
Pages (from-to)463-471
Number of pages9
JournalTaiwanese Journal of Obstetrics and Gynecology
Volume55
Issue number4
DOIs
Publication statusPublished - Aug 1 2016

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Keywords

  • diagnosis
  • leiomyosarcoma
  • treatment
  • uterine sarcoma
  • uterus

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Wen, K. C., Horng, H. C., Wang, P. H., Chen, Y. J., Yen, M. S., Ng, H. T., Chang, Y. H., Chang, Y., Chao, H. T., Chao, K. C., Chuang, C. M., Ho, C. H., Huang, C. Y., Hung, Z. C., Jiang, L. Y., Lau, H. Y., Li, H. Y., Lin, C. Y., Liu, C. H., ... Tsui, K. H. (2016). Uterine sarcoma Part I—Uterine leiomyosarcoma: The Topic Advisory Group systematic review. Taiwanese Journal of Obstetrics and Gynecology, 55(4), 463-471. https://doi.org/10.1016/j.tjog.2016.04.033