Using non-invasive radionuclide imaging to detect esophagitis in patients with gastroesophageal reflux disease

Chang Hu Hsu, Shih Chih Shiun, Nan Yung Hsu, Shung Shung Sun, Albert Kao, Cheng Chun Lee, Cheng Chieh Lin

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Abstract

Background/Aims: The aim of our study was to evaluate technetium-99m tetrofosmin SPECT (single photon emission computed tomography) of the chest as a potential non-invasive method to evaluate esophagitis among gastroesophageal reflux disease patients. Methodology: In this study, we used non-invasive radionuclide imaging technetium-99m tetrofosmin chest SPECT to detect and grade esophagitis in 60 patients with gastroesophageal reflux disease. Results: Based on the endoscopic findings according to the Savary-Miller system, the sensitivity, specificity, and accuracy rates of technetium-99m tetrofosmin chest SPECT in detecting esophagitis were 95.2%, 72.2%, and 88.3%, respectively. The agreement between the endoscopic and technetium-99m tetrofosmin chest SPECT findings was evaluated and found to be good (kappa: 0.633, p <0.001). Conclusions: Non-invasive technetium-99m tetrofosmin chest SPECT has excellent sensitivity and good accuracy as a screen for esophagitis among gastroesophageal reflux disease patients.

Original languageEnglish
Pages (from-to)107-109
Number of pages3
JournalHepato-Gastroenterology
Volume50
Issue number49
Publication statusPublished - Jan 2003
Externally publishedYes

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Keywords

  • Esophagitis
  • Single photon emission computed tomography
  • Technetium-99m tetrofosmin

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Hsu, C. H., Shiun, S. C., Hsu, N. Y., Sun, S. S., Kao, A., Lee, C. C., & Lin, C. C. (2003). Using non-invasive radionuclide imaging to detect esophagitis in patients with gastroesophageal reflux disease. Hepato-Gastroenterology, 50(49), 107-109.