Usefulness of Pulmonary Arterial Flow Discordance to Identify Pulmonary Embolism

Shih Hung Hsiao, Chiu Yen Lee, Shu Mei Chang, Shu Hsin Yang, Shih Kai Lin, Kuan Rau Chiou

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The present study was undertaken to determine the sensitivity and specificity of echocardiography in the diagnosis of pulmonary embolism (PE). The study consisted of 2 stages. First, 600 patients were enrolled to measure bilateral pulmonary blood flow by echocardiography. Using multidetector row computed tomography, 200 subjects were diagnosed with pulmonary hypertension and 100 with defined PE. Another 300 subjects without cardiopulmonary distress served as controls. The time-velocity integral (TVI) and flow volume of both pulmonary arteries were obtained. The percentage differences in bilateral pulmonary arterial TVI (ΔTVI/mean) were 12.0 ± 9.3%, 13.8 ± 12.1%, and 38.6 ± 14.9% for controls, subjects with pulmonary hypertension, and subjects with PE, respectively. The percentage differences in bilateral pulmonary flow (Δflow/mean) were 15.1 ± 11.7%, 17.6 ± 14.9%, and 36.8 ± 17.5% for controls, subjects with pulmonary hypertension, and subjects with PE, respectively. By receiver-operating characteristic curve analysis, the cut-off points for ΔTVI/mean and Δflow/mean to identify PE were 25% and 26.5%, respectively. In the second part of study, the accuracy of ΔTVI/mean and Δflow/mean to screen 300 patients with suspected PE was tested. Echocardiography provided high degrees of sensitivity and specificity for the diagnosis of PE. In conclusion, bilateral pulmonary arterial flow measurement is a simple and useful test to assess the possibility of PE.

Original languageEnglish
Pages (from-to)579-583
Number of pages5
JournalAmerican Journal of Cardiology
Volume99
Issue number4
DOIs
Publication statusPublished - Feb 15 2007
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Usefulness of Pulmonary Arterial Flow Discordance to Identify Pulmonary Embolism'. Together they form a unique fingerprint.

  • Cite this