Use of opioid analgesics or sleeping medication and survival of cancer patients

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Abstract

Purpose of the research: Pain and sleep disturbance have been shown to have a profound influence on the outcomes of cancer treatment. This study sought to determine whether administering opioid analgesics or sleeping medication to cancer patients during their first admission to a hospital is associated with poor prognoses. Methods and sample: We conducted a population-based retrospective cohort study by analyzing data obtained from the National Health Insurance Research Database in Taiwan. The study population comprised cancer patients whose first admission to a hospital for initial cancer treatment was in 2004. Key results: We collected data on 2302 cancer patients. To analyze the effect of opioid analgesic and sleeping medication usage on cancer patient survival, we compared the 3-year survival rates among 4 groups of patients (no use, sleeping medications-only, opioid analgesics-only, both used). The 3-year Kaplan-Meier plots for these 4 groups show that the difference was statistically significant (log rank 48.244, p

Original languageEnglish
Pages (from-to)199-206
Number of pages8
JournalEuropean Journal of Oncology Nursing
Volume19
Issue number3
DOIs
Publication statusPublished - Jun 1 2015

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Keywords

  • Cancer
  • Opioid analgesics
  • Sleeping medications
  • Survival analysis

ASJC Scopus subject areas

  • Oncology(nursing)

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