Use of cardiac troponin T, creatine kinase and its isoform to monitor myocardial injury during radiofrequency ablation for supraventricular tachycardia

Kou Gi Shyu, Jiunn Lee Lin, Jin Jer Chen, Hang Chang

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

To determine whether radiofrequency ablation for supraventricular tachycardia causes significant minor myocardial injury, 16 patients with supraventricular tachycardia undergoing radiofrequency ablation were studied. Cardiac troponin T, creatine kinase and its MB form (CKMB) were measured before, immediately after ablation and every 6 h thereafter for 24 h to detect myocardial injury. Elevation of creatine kinase, CKMB and cardiac troponin T was observed in 6, 4 and 5 patients, respectively. The peak mean creatine kinase concentration was 167 ± 152 IU/l and that of CKMB was 9 ± 6 IU/l. The peak mean cardiac troponin T level was 0.44 ± 0.47 ng/ml. The frequency of elevated measurements was not statistically different among creatine kinase, CKMB and cardiac troponin T. The mean pulse numbers of ablation, mean duration of ablation, radiofrequency current and mean total energy did not differ statistically between those with or without elevated cardiac troponin T. It was concluded that radiofrequency ablation for supraventricular tachycardia indeed caused some minor myocardial injury and the frequency of elevated cardiac troponin T was comparable to that of CKMB.

Original languageEnglish
Pages (from-to)392-395
Number of pages4
JournalCardiology
Volume87
Issue number5
Publication statusPublished - Sep 1996
Externally publishedYes

Fingerprint

Troponin T
Supraventricular Tachycardia
Creatine Kinase
Protein Isoforms
Wounds and Injuries
MB Form Creatine Kinase

Keywords

  • Cardiac troponin T
  • Creatine kinase
  • Myocardial injury
  • Radiofrequency ablation
  • Supraventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Use of cardiac troponin T, creatine kinase and its isoform to monitor myocardial injury during radiofrequency ablation for supraventricular tachycardia. / Shyu, Kou Gi; Lin, Jiunn Lee; Chen, Jin Jer; Chang, Hang.

In: Cardiology, Vol. 87, No. 5, 09.1996, p. 392-395.

Research output: Contribution to journalArticle

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AB - To determine whether radiofrequency ablation for supraventricular tachycardia causes significant minor myocardial injury, 16 patients with supraventricular tachycardia undergoing radiofrequency ablation were studied. Cardiac troponin T, creatine kinase and its MB form (CKMB) were measured before, immediately after ablation and every 6 h thereafter for 24 h to detect myocardial injury. Elevation of creatine kinase, CKMB and cardiac troponin T was observed in 6, 4 and 5 patients, respectively. The peak mean creatine kinase concentration was 167 ± 152 IU/l and that of CKMB was 9 ± 6 IU/l. The peak mean cardiac troponin T level was 0.44 ± 0.47 ng/ml. The frequency of elevated measurements was not statistically different among creatine kinase, CKMB and cardiac troponin T. The mean pulse numbers of ablation, mean duration of ablation, radiofrequency current and mean total energy did not differ statistically between those with or without elevated cardiac troponin T. It was concluded that radiofrequency ablation for supraventricular tachycardia indeed caused some minor myocardial injury and the frequency of elevated cardiac troponin T was comparable to that of CKMB.

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