Abstract
Objective: Despite some epidemiologic research demonstrating a positive relationship between serum uric acid (SUA) levels and the prevalence of metabolic syndrome (MetS), prospective data on SUA as a predictor of MetS incidence are limited. Methods: The authors examined SUA as a risk marker for incident MetS in a prospective study of 3857 subjects who were free of MetS at baseline recruitment. Hyperuricemia was defined as SUA ≥7.7. mg/dL for men and ≥6.6. mg/dL for women. The MetS was defined according to a unified criteria set by several major organizations. Results: During a mean follow-up of 5.41 years, 476 participants developed MetS. A significantly stepwise increase in the incidence of MetS across tertiles of SUA was observed in the whole group (p for trend
| Original language | English |
|---|---|
| Pages (from-to) | 525-531 |
| Number of pages | 7 |
| Journal | Atherosclerosis |
| Volume | 220 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2012 |
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Keywords
- Cohort study
- Hyperuricemia
- Metabolic syndrome
- Uric acid
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Uric acid level as a risk marker for metabolic syndrome : A Chinese cohort study. / Yang, Tsan; Chu, Chi Hong; Bai, Chyi Huey; You, San Lin; Chou, Yu Ching; Chou, Wan Yun; Chien, Kuo Liong; Hwang, Lee Ching; Su, Ta Chen; Tseng, Chin Hsiao; Sun, Chien An.
In: Atherosclerosis, Vol. 220, No. 2, 02.2012, p. 525-531.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Uric acid level as a risk marker for metabolic syndrome
T2 - A Chinese cohort study
AU - Yang, Tsan
AU - Chu, Chi Hong
AU - Bai, Chyi Huey
AU - You, San Lin
AU - Chou, Yu Ching
AU - Chou, Wan Yun
AU - Chien, Kuo Liong
AU - Hwang, Lee Ching
AU - Su, Ta Chen
AU - Tseng, Chin Hsiao
AU - Sun, Chien An
PY - 2012/2
Y1 - 2012/2
N2 - Objective: Despite some epidemiologic research demonstrating a positive relationship between serum uric acid (SUA) levels and the prevalence of metabolic syndrome (MetS), prospective data on SUA as a predictor of MetS incidence are limited. Methods: The authors examined SUA as a risk marker for incident MetS in a prospective study of 3857 subjects who were free of MetS at baseline recruitment. Hyperuricemia was defined as SUA ≥7.7. mg/dL for men and ≥6.6. mg/dL for women. The MetS was defined according to a unified criteria set by several major organizations. Results: During a mean follow-up of 5.41 years, 476 participants developed MetS. A significantly stepwise increase in the incidence of MetS across tertiles of SUA was observed in the whole group (p for trend
AB - Objective: Despite some epidemiologic research demonstrating a positive relationship between serum uric acid (SUA) levels and the prevalence of metabolic syndrome (MetS), prospective data on SUA as a predictor of MetS incidence are limited. Methods: The authors examined SUA as a risk marker for incident MetS in a prospective study of 3857 subjects who were free of MetS at baseline recruitment. Hyperuricemia was defined as SUA ≥7.7. mg/dL for men and ≥6.6. mg/dL for women. The MetS was defined according to a unified criteria set by several major organizations. Results: During a mean follow-up of 5.41 years, 476 participants developed MetS. A significantly stepwise increase in the incidence of MetS across tertiles of SUA was observed in the whole group (p for trend
KW - Cohort study
KW - Hyperuricemia
KW - Metabolic syndrome
KW - Uric acid
UR - http://www.scopus.com/inward/record.url?scp=84855932028&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84855932028&partnerID=8YFLogxK
U2 - 10.1016/j.atherosclerosis.2011.11.014
DO - 10.1016/j.atherosclerosis.2011.11.014
M3 - Article
C2 - 22154195
AN - SCOPUS:84855932028
VL - 220
SP - 525
EP - 531
JO - Atherosclerosis
JF - Atherosclerosis
SN - 0021-9150
IS - 2
ER -