Uremic tumoral calcinosis in patients on peritoneal dialysis

Clinical, radiologic, and laboratory features

Hung Yi Chu, Pauling Chu, Yuh Feng Lin, Heng Kuang Chou, Shih Hua Lin

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Background: Uremic tumoral calcinosis (UTC) has been analyzed in uremic patients on hemodialysis, but little is known about UTC in peritoneal dialysis (PD). In this study, we aimed to characterize UTC in uremic patients on PD. Methods: We retrospectively reviewed uremic patients on PD who developed UTC over a 9-year period. Clinical, radiologic, and laboratory features; treatments; and outcomes in those patients were assessed. One of the patients (case 7) is described as a case example. Results: The study enrolled 7 patients with a mean age of 41 years. Mean time from PD to UTC was 45.3 months. All patients were anuric but adequately dialyzed. Cardinal symptoms were local tenderness and limited range of joint motion. Lesions were mostly multifocal (n = 6) and predominantly involved shoulders, hands, feet, hips, and wrists. Metatarsophalangeal joint UTC was misdiagnosed as tophaceous gout in 2 patients. Main laboratory findings were hyperphosphatemia (7.9 ± 0.8 mg 2/dL 2), high Ca×P product [>65 mg 2/dL 2 (range: 81.1 ± 11.5 mg2/dL2)], secondary hyperparathyroidism (SHPT) with various levels of intact parathyroid hormone (iPTH: 592.2 ± 315.2 pg/mL;

Original languageEnglish
Pages (from-to)430-439
Number of pages10
JournalPeritoneal Dialysis International
Volume31
Issue number4
DOIs
Publication statusPublished - Jul 2011

Fingerprint

Calcinosis
Peritoneal Dialysis
Metatarsophalangeal Joint
Hyperphosphatemia
Secondary Hyperparathyroidism
Gout
Articular Range of Motion
Diagnostic Errors
Wrist
Parathyroid Hormone
Renal Dialysis
Hip
Foot
Hand

Keywords

  • Calcium phosphate
  • Parathyroidectomy
  • Uremic tumoral calcinosis

ASJC Scopus subject areas

  • Nephrology

Cite this

Uremic tumoral calcinosis in patients on peritoneal dialysis : Clinical, radiologic, and laboratory features. / Chu, Hung Yi; Chu, Pauling; Lin, Yuh Feng; Chou, Heng Kuang; Lin, Shih Hua.

In: Peritoneal Dialysis International, Vol. 31, No. 4, 07.2011, p. 430-439.

Research output: Contribution to journalArticle

Chu, Hung Yi ; Chu, Pauling ; Lin, Yuh Feng ; Chou, Heng Kuang ; Lin, Shih Hua. / Uremic tumoral calcinosis in patients on peritoneal dialysis : Clinical, radiologic, and laboratory features. In: Peritoneal Dialysis International. 2011 ; Vol. 31, No. 4. pp. 430-439.
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