Update on Flashlamp Pumped Pulsed Dye Laser Treatment for Port Wine Stains (Capillary Malformation) Patients

Yen Chang Hsiao, Cheng Jen Chang

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Background and Aims: Currently, the method of choice for the treatment of port-wine stains is laser photocoagulation. Because of evolving treatment options, it is no longer enough for port-wine stains merely to be lightened through laser treatment. The best course of management consists of the most appropriate laser that will produce the most complete clearing of a lesion in the fewest treatment sessions with the least morbidity. The goal is generally accomplished with the use of yellow-light lasers. Materials (Subjects) and Methods: Absorption of laser energy by melanin causes localized heating in the epidermis, which may, if not controlled, produce permanent complications such as hypertrophic scarring or dyspigmentation. Refinements of the results can be achieved by using the flashlamp-pumped pulsed dye laser (FLPDL) in conjunction with the cryogen spray cooling (CSC) system. In our related studies, the infrared thermal image instrument is used for doctors in determining the optimum laser light dosage and preventing the side effects caused by FLPDL. Topic application of angiogenesis inhibitor (Imiquimod) in conjunction with pulsed dye laser treatment for the PWS patients has been assessed for improvement of FLPDL treatment. Results: We present the clinical effect of FLPDL, and the efficacy and safety of cooled laser treatment of PWS birthmarks. Our clinical outcome in the laser treatment of patients with PWS has been achieved to maximize thermal impact on targeted vessels, while minimizing adverse complications. Conclusions: CSC in conjunction with FLPDL can improve the treatment of PWS. The infrared image instrument is helpful for doctors in determining the optimum laser light dosage. Topic application of angiogenesis inhibitor (Imiquimod) in conjunction with laser treatment for the PWS patients is promising in the near future.

Original languageEnglish
Pages (from-to)265-272
Number of pages8
JournalLaser Therapy
Volume20
Issue number4
DOIs
Publication statusPublished - 2011
Externally publishedYes

Fingerprint

Port-Wine Stain
Dye Lasers
Wine
Dye lasers
Pulsed lasers
Lasers
imiquimod
Therapeutics
Angiogenesis Inhibitors
Light
Hot Temperature
Capillary Malformations, Congenital, 1
Melanin
Infrared radiation
Light Coagulation
Melanins
Cooling systems
Epidermis
Heating
Cicatrix

Keywords

  • Angiogenesis inhibitor
  • Cryogen spray cooling (CSC)
  • Flashlamp-pumped pulsed dye laser (FLPDL)
  • Infrared thermal image instrument
  • Port-wine stains (PWS)

ASJC Scopus subject areas

  • Surgery
  • Biomedical Engineering

Cite this

Update on Flashlamp Pumped Pulsed Dye Laser Treatment for Port Wine Stains (Capillary Malformation) Patients. / Hsiao, Yen Chang; Chang, Cheng Jen.

In: Laser Therapy, Vol. 20, No. 4, 2011, p. 265-272.

Research output: Contribution to journalReview article

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abstract = "Background and Aims: Currently, the method of choice for the treatment of port-wine stains is laser photocoagulation. Because of evolving treatment options, it is no longer enough for port-wine stains merely to be lightened through laser treatment. The best course of management consists of the most appropriate laser that will produce the most complete clearing of a lesion in the fewest treatment sessions with the least morbidity. The goal is generally accomplished with the use of yellow-light lasers. Materials (Subjects) and Methods: Absorption of laser energy by melanin causes localized heating in the epidermis, which may, if not controlled, produce permanent complications such as hypertrophic scarring or dyspigmentation. Refinements of the results can be achieved by using the flashlamp-pumped pulsed dye laser (FLPDL) in conjunction with the cryogen spray cooling (CSC) system. In our related studies, the infrared thermal image instrument is used for doctors in determining the optimum laser light dosage and preventing the side effects caused by FLPDL. Topic application of angiogenesis inhibitor (Imiquimod) in conjunction with pulsed dye laser treatment for the PWS patients has been assessed for improvement of FLPDL treatment. Results: We present the clinical effect of FLPDL, and the efficacy and safety of cooled laser treatment of PWS birthmarks. Our clinical outcome in the laser treatment of patients with PWS has been achieved to maximize thermal impact on targeted vessels, while minimizing adverse complications. Conclusions: CSC in conjunction with FLPDL can improve the treatment of PWS. The infrared image instrument is helpful for doctors in determining the optimum laser light dosage. Topic application of angiogenesis inhibitor (Imiquimod) in conjunction with laser treatment for the PWS patients is promising in the near future.",
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