Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion

Chih Hsin Lee, Jann Yuan Wang, Kuo Liang Huang, Hung Wen Chiu, Tsung Ching Fei, Tsui Shia Chen, Hung Chang

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent. This study was conducted to determine whether pulse contour-derived cardiac output truly reflects rapid hemodynamic changes. Methods: Hemorrhagic shock was created in seven anesthetized piglets by continuous blood withdrawal at a rate of 1 mL • kg • min for 20 minutes. Volume expansion with 10% hydroxyethyl starch 8 mL • kg was then administered for 5 minutes. Pulse contour-derived and thermodilution- derived hemodynamic parameters were compared. Results: Baseline thermodilution-derived cardiac index was 3.2 ± 0.4 L • min • M. After exsanguination, it decreased to 2.1 ± 0.3 L • min • M while pulse contour-derived cardiac index increased to 4.4 ± 0.4 L • min • M (p value

Original languageEnglish
Pages (from-to)1357-1361
Number of pages5
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume68
Issue number6
DOIs
Publication statusPublished - Jun 2010
Externally publishedYes

Fingerprint

Hemorrhagic Shock
Cardiac Output
Pulse
Hemodynamics
Thermodilution
Exsanguination
Critical Care
Starch

Keywords

  • Arterial pressure
  • Cardiac output
  • Hemodynamic monitoring
  • Model
  • Pig
  • Thermodilution

ASJC Scopus subject areas

  • Surgery
  • Critical Care and Intensive Care Medicine

Cite this

Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion. / Lee, Chih Hsin; Wang, Jann Yuan; Huang, Kuo Liang; Chiu, Hung Wen; Fei, Tsung Ching; Chen, Tsui Shia; Chang, Hung.

In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 68, No. 6, 06.2010, p. 1357-1361.

Research output: Contribution to journalArticle

@article{d18503ef47954545b0f3a407ac6f26da,
title = "Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion",
abstract = "Background: Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent. This study was conducted to determine whether pulse contour-derived cardiac output truly reflects rapid hemodynamic changes. Methods: Hemorrhagic shock was created in seven anesthetized piglets by continuous blood withdrawal at a rate of 1 mL • kg • min for 20 minutes. Volume expansion with 10{\%} hydroxyethyl starch 8 mL • kg was then administered for 5 minutes. Pulse contour-derived and thermodilution- derived hemodynamic parameters were compared. Results: Baseline thermodilution-derived cardiac index was 3.2 ± 0.4 L • min • M. After exsanguination, it decreased to 2.1 ± 0.3 L • min • M while pulse contour-derived cardiac index increased to 4.4 ± 0.4 L • min • M (p value",
keywords = "Arterial pressure, Cardiac output, Hemodynamic monitoring, Model, Pig, Thermodilution",
author = "Lee, {Chih Hsin} and Wang, {Jann Yuan} and Huang, {Kuo Liang} and Chiu, {Hung Wen} and Fei, {Tsung Ching} and Chen, {Tsui Shia} and Hung Chang",
year = "2010",
month = "6",
doi = "10.1097/TA.0b013e3181d7685a",
language = "English",
volume = "68",
pages = "1357--1361",
journal = "Journal of Trauma and Acute Care Surgery",
issn = "2163-0755",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion

AU - Lee, Chih Hsin

AU - Wang, Jann Yuan

AU - Huang, Kuo Liang

AU - Chiu, Hung Wen

AU - Fei, Tsung Ching

AU - Chen, Tsui Shia

AU - Chang, Hung

PY - 2010/6

Y1 - 2010/6

N2 - Background: Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent. This study was conducted to determine whether pulse contour-derived cardiac output truly reflects rapid hemodynamic changes. Methods: Hemorrhagic shock was created in seven anesthetized piglets by continuous blood withdrawal at a rate of 1 mL • kg • min for 20 minutes. Volume expansion with 10% hydroxyethyl starch 8 mL • kg was then administered for 5 minutes. Pulse contour-derived and thermodilution- derived hemodynamic parameters were compared. Results: Baseline thermodilution-derived cardiac index was 3.2 ± 0.4 L • min • M. After exsanguination, it decreased to 2.1 ± 0.3 L • min • M while pulse contour-derived cardiac index increased to 4.4 ± 0.4 L • min • M (p value

AB - Background: Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent. This study was conducted to determine whether pulse contour-derived cardiac output truly reflects rapid hemodynamic changes. Methods: Hemorrhagic shock was created in seven anesthetized piglets by continuous blood withdrawal at a rate of 1 mL • kg • min for 20 minutes. Volume expansion with 10% hydroxyethyl starch 8 mL • kg was then administered for 5 minutes. Pulse contour-derived and thermodilution- derived hemodynamic parameters were compared. Results: Baseline thermodilution-derived cardiac index was 3.2 ± 0.4 L • min • M. After exsanguination, it decreased to 2.1 ± 0.3 L • min • M while pulse contour-derived cardiac index increased to 4.4 ± 0.4 L • min • M (p value

KW - Arterial pressure

KW - Cardiac output

KW - Hemodynamic monitoring

KW - Model

KW - Pig

KW - Thermodilution

UR - http://www.scopus.com/inward/record.url?scp=77953734974&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953734974&partnerID=8YFLogxK

U2 - 10.1097/TA.0b013e3181d7685a

DO - 10.1097/TA.0b013e3181d7685a

M3 - Article

VL - 68

SP - 1357

EP - 1361

JO - Journal of Trauma and Acute Care Surgery

JF - Journal of Trauma and Acute Care Surgery

SN - 2163-0755

IS - 6

ER -