Unilateral optic nerve leukemic infiltration with sudden vision loss heralding a systemic relapse of acute lymphoblastic leukemia

Hsuen Fu Lin, Ming Shen Dai, Woei Yau Kao, Tsu Yi Chao

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We describe a 21-year-old patient with acute lymphoblastic leukemia (ALL) who achieved complete remission after induction, consolidation chemotherapy and central nervous system prophylaxis with intrathecal methotrexate and cranial irradiation. He developed a relapse of ALL 6 months after remission. This presented as isolated optic nerve infiltration with leukemic cells and sudden loss of ipsilateral vision prior to systemic relapse. Subsequent surgical intervention, salvage chemoradiotherapy and further allogeneic stem cell transplantation did not induce disease remission or restore his visual acuity.

Original languageEnglish
Pages (from-to)97-100
Number of pages4
JournalJournal of Medical Sciences (Taiwan)
Volume25
Issue number2
Publication statusPublished - Apr 2005
Externally publishedYes

Keywords

  • ALL
  • CNS relapse
  • Leukemic infiltration
  • Optic neuropathy
  • Vision loss

ASJC Scopus subject areas

  • Medicine(all)

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