Ultrastructural identification of a sympathetic component in the hypoglossal nerve of hamsters using experimental degeneration and horseradish peroxidase methods

Chi Y. Tseng, I. H. Wei, Hung Ming Chang, June Horng Lue, Chen Yuan Wen, Jeng Yung Shieh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We employed experimental degeneration, tract-tracing with wheatgerm agglutinin conjugated with horseradish peroxidase (WGA-HRP) and electron microscopy to explore the postganglionic sympathetic fibers in the hypoglossal nerve of hamsters. Quantitative results of normal untreated animals at the electron microscopic level showed the existence of unmyelinated fibers, which made up about 20% of the total fibers in the nerve, being more numerous on the left side. The nerve fibers were preferentially distributed at the periphery of the nerve. Following superior cervical ganglionectomy, most of the unmyelinated fibers underwent degenerative changes. Tract-tracing studies showed that some of the unmyelinated fibers were labeled by WGA-HRP injected into the superior cervical ganglion (SCG). It is suggested that the unmyelinated fibers represent the postganglionic sympathetic fibers originated from the SCG.

Original languageEnglish
Pages (from-to)117-125
Number of pages9
JournalCells Tissues Organs
Volume180
Issue number2
DOIs
Publication statusPublished - 2005
Externally publishedYes

Fingerprint

Postganglionic Sympathetic Fibers
Hypoglossal Nerve
Superior Cervical Ganglion
Agglutinins
Horseradish Peroxidase
Nerve Fibers
Cricetinae
Ganglionectomy
Electron Microscopy
Electrons

Keywords

  • Degeneration
  • Hamster
  • Horseradish peroxidase
  • Hypoglossal nerve
  • Postganglionic sympathetic fibers
  • Superior cervical ganglion

ASJC Scopus subject areas

  • Anatomy

Cite this

Ultrastructural identification of a sympathetic component in the hypoglossal nerve of hamsters using experimental degeneration and horseradish peroxidase methods. / Tseng, Chi Y.; Wei, I. H.; Chang, Hung Ming; Lue, June Horng; Wen, Chen Yuan; Shieh, Jeng Yung.

In: Cells Tissues Organs, Vol. 180, No. 2, 2005, p. 117-125.

Research output: Contribution to journalArticle

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AU - Lue, June Horng

AU - Wen, Chen Yuan

AU - Shieh, Jeng Yung

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