Two-stage revision hip arthroplasty for infection with a custom-made, antibiotic-loaded, cement prosthesis as an interim spacer

Pang Hsin Hsieh, Lih Huei Chen, Chi Hwa Chen, Mel S. Lee, Wen E. Yang, Chun Hsiung Shih

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Background: Two-stage reconstruction is a well-recognized treatment for deep infection of hip joint implants. The purpose of the study was to report the results of our treatment using a standardized protocol. Methods: Forty-two consecutive patients with deep infection of the hip prosthesis were treated according to a prospective, two-stage resection/reimplantation protocol. Between stages, a custom-made, antibiotic-loaded, cement prosthesis was implanted as an interim spacer. Results: Infection was eradicated in 41 patients after the first-stage operation. Thirty-six patients remained with the ability to walk with the interim cement prosthesis. For 40 patients who underwent reimplantation, recurrence of infection was observed in only 1 patient at an average of 55.2 months' follow-up. Conclusion: We have found that our two-stage treatment protocol is a reliable approach for the management of infected hip prostheses. It is effective for eradicating infection and for providing a mobile and functional joint through the treatment course.

Original languageEnglish
Pages (from-to)1247-1252
Number of pages6
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume56
Issue number6
Publication statusPublished - Jun 2004
Externally publishedYes

Fingerprint

Arthroplasty
Prostheses and Implants
Hip
Anti-Bacterial Agents
Hip Prosthesis
Infection
Replantation
Hip Joint
Clinical Protocols
Therapeutics
Joints
Recurrence

Keywords

  • Antibiotic cement
  • Hip arthroplasty
  • Infection

ASJC Scopus subject areas

  • Surgery

Cite this

Two-stage revision hip arthroplasty for infection with a custom-made, antibiotic-loaded, cement prosthesis as an interim spacer. / Hsieh, Pang Hsin; Chen, Lih Huei; Chen, Chi Hwa; Lee, Mel S.; Yang, Wen E.; Shih, Chun Hsiung.

In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 56, No. 6, 06.2004, p. 1247-1252.

Research output: Contribution to journalArticle

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AU - Hsieh, Pang Hsin

AU - Chen, Lih Huei

AU - Chen, Chi Hwa

AU - Lee, Mel S.

AU - Yang, Wen E.

AU - Shih, Chun Hsiung

PY - 2004/6

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N2 - Background: Two-stage reconstruction is a well-recognized treatment for deep infection of hip joint implants. The purpose of the study was to report the results of our treatment using a standardized protocol. Methods: Forty-two consecutive patients with deep infection of the hip prosthesis were treated according to a prospective, two-stage resection/reimplantation protocol. Between stages, a custom-made, antibiotic-loaded, cement prosthesis was implanted as an interim spacer. Results: Infection was eradicated in 41 patients after the first-stage operation. Thirty-six patients remained with the ability to walk with the interim cement prosthesis. For 40 patients who underwent reimplantation, recurrence of infection was observed in only 1 patient at an average of 55.2 months' follow-up. Conclusion: We have found that our two-stage treatment protocol is a reliable approach for the management of infected hip prostheses. It is effective for eradicating infection and for providing a mobile and functional joint through the treatment course.

AB - Background: Two-stage reconstruction is a well-recognized treatment for deep infection of hip joint implants. The purpose of the study was to report the results of our treatment using a standardized protocol. Methods: Forty-two consecutive patients with deep infection of the hip prosthesis were treated according to a prospective, two-stage resection/reimplantation protocol. Between stages, a custom-made, antibiotic-loaded, cement prosthesis was implanted as an interim spacer. Results: Infection was eradicated in 41 patients after the first-stage operation. Thirty-six patients remained with the ability to walk with the interim cement prosthesis. For 40 patients who underwent reimplantation, recurrence of infection was observed in only 1 patient at an average of 55.2 months' follow-up. Conclusion: We have found that our two-stage treatment protocol is a reliable approach for the management of infected hip prostheses. It is effective for eradicating infection and for providing a mobile and functional joint through the treatment course.

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