Tuberculosis in maintenance dialysis patients

Kang Ju Chou, Hua Chang Fang, Kuan Jen Bai, Shang Jyh Hwang, Wu Chang Yang, Hsiao Min Chung

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

In this investigation, we tried to find the incidence and characteristics of tuberculosis (TB) in dialysis patients previously found only in a small number of cases. We collected the cases of newly diagnosed TB patients in Taiwan during 1997. Simultaneously, all dialysis patients were collected and matched with the TB cases to identify the dialysis patients who had also contracted TB. The annual incidence of the dialysis population was 493.4/100,000, 6.9 times that of the general population (71.1/100,000). The annual incidence for the male dialysis population was 573.3, the incidence was 479.2 for the female dialysis population. The incidence for the general population was 97.1 and 43.7/100,000, respectively. Although the 1-year mortality rate due to TB (1.7 vs. 1.9%, p > 0.05) was similar in both populations, the non-TB mortality was much higher in the dialysis population than that in the general population (25.6 vs. 11.1%, p <0.05). Finally, the 1-year mortality rate of dialysis patients with TB is 3.3 times higher than that in dialysis patients without TB (27.3 vs. 8.3%, p <0.05). The findings suggest that uremia modifies the behavior of TB, jeopardizes female and younger dialysis patients, poses a higher risk of extrapulmonary dissemination, and predicts a higher overall mortality.

Original languageEnglish
Pages (from-to)138-143
Number of pages6
JournalNephron
Volume88
Issue number2
DOIs
Publication statusPublished - 2001

Fingerprint

Dialysis
Tuberculosis
Maintenance
Population
Incidence
Mortality
Uremia
Taiwan

Keywords

  • Dialysis
  • Tuberculosis
  • Uremia

ASJC Scopus subject areas

  • Nephrology

Cite this

Chou, K. J., Fang, H. C., Bai, K. J., Hwang, S. J., Yang, W. C., & Chung, H. M. (2001). Tuberculosis in maintenance dialysis patients. Nephron, 88(2), 138-143. https://doi.org/10.1159/000045974

Tuberculosis in maintenance dialysis patients. / Chou, Kang Ju; Fang, Hua Chang; Bai, Kuan Jen; Hwang, Shang Jyh; Yang, Wu Chang; Chung, Hsiao Min.

In: Nephron, Vol. 88, No. 2, 2001, p. 138-143.

Research output: Contribution to journalArticle

Chou, KJ, Fang, HC, Bai, KJ, Hwang, SJ, Yang, WC & Chung, HM 2001, 'Tuberculosis in maintenance dialysis patients', Nephron, vol. 88, no. 2, pp. 138-143. https://doi.org/10.1159/000045974
Chou KJ, Fang HC, Bai KJ, Hwang SJ, Yang WC, Chung HM. Tuberculosis in maintenance dialysis patients. Nephron. 2001;88(2):138-143. https://doi.org/10.1159/000045974
Chou, Kang Ju ; Fang, Hua Chang ; Bai, Kuan Jen ; Hwang, Shang Jyh ; Yang, Wu Chang ; Chung, Hsiao Min. / Tuberculosis in maintenance dialysis patients. In: Nephron. 2001 ; Vol. 88, No. 2. pp. 138-143.
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