Hemophagocytic syndrome (HPS) is a clinicopathological reflection of uncontrolled activation of macrophages. To our knowledge, only a few cases of tuberculosis-associated HPS in hemodialysis have been reported in the English literature. We report a case of tuberculosis-associated HPS during hemodialysis. Bone marrow aspiration showed histiocytosis with hemophagocytosis; in addition, results of acid-fast staining and polymerase chain reaction showed the presence of acid-fast bacilli. Mycobacterium tuberculosis was subsequently cultured from sputum. The patient received late treatment with antituberculosis agents combined with intravenous immunoglobulin and had a poor response. On the basis of the results in this case, we recommend early bone marrow and tuberculous examination for patients undergoing maintenance hemodialysis who have fever of unknown origin.
|Number of pages||3|
|Journal||International Journal of Hematology|
|Publication status||Published - May 2004|
- Fever of unknown origin
- Hemophagocytic syndrome
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