Abstract

Background and Purpose-The aim of this study is to estimate the risk of ischemic stroke during a 3-year follow-up period after a tuberculosis diagnosis using a nationwide, population-based study and a retrospective cohort design. Method-The study cohort comprised 2283 patients who had received treatment for tuberculosis, except tuberculosis of the meninges and central nervous system, between 2000 and 2003; 6849 randomly selected subjects comprised the comparison cohort. Cox proportional hazard regressions were performed as a means of comparing the 3-year ischemic stroke-free survival rate between these 2 cohorts. Results-Of the 9132 sampled patients, 392 (4.3%) experienced ischemic stroke during the 3-year follow-up period, including 136 (6.0% of the tuberculosis patients) from the study cohort and 256 (3.7%) from the comparison cohort. After adjusting for patient age, gender, hypertension, diabetes, coronary heart disease, hyperlipidemia, malignancy, monthly income, and the geographical region and urbanization level of the community in which the patient resided, the hazard ratio of ischemic stroke for tuberculosis patients was 1.52-times (95% CI, 1.21-1.91; P

Original languageEnglish
Pages (from-to)244-249
Number of pages6
JournalStroke
Volume41
Issue number2
DOIs
Publication statusPublished - Feb 2010

Fingerprint

Tuberculosis
Stroke
Central Nervous System Tuberculosis
Cohort Studies
Meninges
Urbanization
Hyperlipidemias
Coronary Disease
Survival Rate
Retrospective Studies
Hypertension
Population
Neoplasms
Therapeutics

Keywords

  • Ischemic stroke
  • Stroke
  • Tuberculosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialised Nursing
  • Medicine(all)

Cite this

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title = "Tuberculosis and the risk of ischemic stroke: A 3-year follow-up study",
abstract = "Background and Purpose-The aim of this study is to estimate the risk of ischemic stroke during a 3-year follow-up period after a tuberculosis diagnosis using a nationwide, population-based study and a retrospective cohort design. Method-The study cohort comprised 2283 patients who had received treatment for tuberculosis, except tuberculosis of the meninges and central nervous system, between 2000 and 2003; 6849 randomly selected subjects comprised the comparison cohort. Cox proportional hazard regressions were performed as a means of comparing the 3-year ischemic stroke-free survival rate between these 2 cohorts. Results-Of the 9132 sampled patients, 392 (4.3{\%}) experienced ischemic stroke during the 3-year follow-up period, including 136 (6.0{\%} of the tuberculosis patients) from the study cohort and 256 (3.7{\%}) from the comparison cohort. After adjusting for patient age, gender, hypertension, diabetes, coronary heart disease, hyperlipidemia, malignancy, monthly income, and the geographical region and urbanization level of the community in which the patient resided, the hazard ratio of ischemic stroke for tuberculosis patients was 1.52-times (95{\%} CI, 1.21-1.91; P",
keywords = "Ischemic stroke, Stroke, Tuberculosis, Ischemic stroke, Stroke, Tuberculosis case management",
author = "Sheu, {Jau Jiuan} and Chiou, {Hung Yi} and Kang, {Jiunn Horng} and Chen, {Yi Hua} and Lin, {Herng Ching}",
year = "2010",
month = "2",
doi = "10.1161/STROKEAHA.109.567735",
language = "English",
volume = "41",
pages = "244--249",
journal = "Stroke",
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T1 - Tuberculosis and the risk of ischemic stroke

T2 - A 3-year follow-up study

AU - Sheu, Jau Jiuan

AU - Chiou, Hung Yi

AU - Kang, Jiunn Horng

AU - Chen, Yi Hua

AU - Lin, Herng Ching

PY - 2010/2

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N2 - Background and Purpose-The aim of this study is to estimate the risk of ischemic stroke during a 3-year follow-up period after a tuberculosis diagnosis using a nationwide, population-based study and a retrospective cohort design. Method-The study cohort comprised 2283 patients who had received treatment for tuberculosis, except tuberculosis of the meninges and central nervous system, between 2000 and 2003; 6849 randomly selected subjects comprised the comparison cohort. Cox proportional hazard regressions were performed as a means of comparing the 3-year ischemic stroke-free survival rate between these 2 cohorts. Results-Of the 9132 sampled patients, 392 (4.3%) experienced ischemic stroke during the 3-year follow-up period, including 136 (6.0% of the tuberculosis patients) from the study cohort and 256 (3.7%) from the comparison cohort. After adjusting for patient age, gender, hypertension, diabetes, coronary heart disease, hyperlipidemia, malignancy, monthly income, and the geographical region and urbanization level of the community in which the patient resided, the hazard ratio of ischemic stroke for tuberculosis patients was 1.52-times (95% CI, 1.21-1.91; P

AB - Background and Purpose-The aim of this study is to estimate the risk of ischemic stroke during a 3-year follow-up period after a tuberculosis diagnosis using a nationwide, population-based study and a retrospective cohort design. Method-The study cohort comprised 2283 patients who had received treatment for tuberculosis, except tuberculosis of the meninges and central nervous system, between 2000 and 2003; 6849 randomly selected subjects comprised the comparison cohort. Cox proportional hazard regressions were performed as a means of comparing the 3-year ischemic stroke-free survival rate between these 2 cohorts. Results-Of the 9132 sampled patients, 392 (4.3%) experienced ischemic stroke during the 3-year follow-up period, including 136 (6.0% of the tuberculosis patients) from the study cohort and 256 (3.7%) from the comparison cohort. After adjusting for patient age, gender, hypertension, diabetes, coronary heart disease, hyperlipidemia, malignancy, monthly income, and the geographical region and urbanization level of the community in which the patient resided, the hazard ratio of ischemic stroke for tuberculosis patients was 1.52-times (95% CI, 1.21-1.91; P

KW - Ischemic stroke

KW - Stroke

KW - Tuberculosis

KW - Ischemic stroke

KW - Stroke

KW - Tuberculosis case management

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