TSOC-HFrEF registry: A registry of hospitalized patients with decompensated systolic heart failure: Description of population and management

Chun Chieh Wang, Hung Yu Chang, Wei Hsian Yin, Yen Wen Wu, Pao Hsien Chu, Chih Cheng Wu, Chih Hsin Hsu, Ming Shien Wen, Wen Chol Voon, Wei Shiang Lin, Jin Long Huang, Shyh Ming Chen, Ning I. Yang, Heng Chia Chang, Kuan Cheng Chang, Shih Hsien Sung, Kou Gi Shyu, Jiunn Lee Lin, Guang Yuan Mar, Kuei Chuan ChanJen Yuan Kuo, Ji Hung Wang, Zhih Cherng Chen, Wei Kung Tseng, Wen Jin Cherng

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Introduction: Heart failure (HF) is a medical condition with a rapidly increasing incidence both in Taiwan and worldwide. The objective of the TSOC-HFrEF registry was to assess epidemiology, etiology, clinical management, and outcomes in a large sample of hospitalized patients presenting with acute decompensated systolic HF. Methods: The TSOC-HFrEF registry was a prospective, multicenter, observational survey of patients presenting to 21 medical centers or teaching hospitals in Taiwan. Hospitalized patients with either acute new-onset HF or acute decompensation of chronic HFrEF were enrolled. Data including demographic characteristics, medical history, primary etiology of HF, precipitating factors for HF hospitalization, presenting symptoms and signs, diagnostic and treatment procedures, in-hospital mortality, length of stay, and dischargemedications,were collected and analyzed. Results: A total of 1509 patients were enrolled into the registry by the end of October 2014, with a mean age of 64 years (72% were male). Ischemic cardiomyopathy and dilated cardiomyopathy were diagnosed in 44% and 33% of patients, respectively. Coronary artery disease, hypertension, diabetes, and chronic renal insufficiency were the common comorbid conditions. Acute coronary syndrome, non-compliant to treatment, and concurrent infection were themajor precipitating factors for acute decompensation. The median length of hospital stay was 8 days, and the in-hospital mortality rate was 2.4%. At discharge, 62% of patients were prescribed either angiotensinconverting enzyme-inhibitors or angiotensin receptor blockers, 60% were prescribed beta-blockers, and 49% were prescribed mineralocorticoid receptor antagonists. Conclusions: The TSOC-HFrEF registry provided important insights into the current clinical characteristics and management of hospitalized decompensated systolic HF patients in Taiwan. One important observation was that adherence to guideline-directed medical therapy was suboptimal.

Original languageEnglish
Pages (from-to)400-411
Number of pages12
JournalActa Cardiologica Sinica
Volume32
Issue number4
DOIs
Publication statusPublished - Jul 1 2016
Externally publishedYes

Fingerprint

Systolic Heart Failure
Registries
Population
Heart Failure
Taiwan
Precipitating Factors
Length of Stay
Hospital Mortality
Mineralocorticoid Receptor Antagonists
Guideline Adherence
Angiotensin Receptor Antagonists
Dilated Cardiomyopathy
Enzyme Inhibitors
Acute Coronary Syndrome
Cardiomyopathies
Chronic Renal Insufficiency
Teaching Hospitals
Signs and Symptoms
Coronary Artery Disease
Epidemiology

Keywords

  • Beta-blocker
  • Guideline
  • Heart failure
  • Renin-angiotensin system blocker
  • Taiwan
  • Treatment

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

TSOC-HFrEF registry : A registry of hospitalized patients with decompensated systolic heart failure: Description of population and management. / Wang, Chun Chieh; Chang, Hung Yu; Yin, Wei Hsian; Wu, Yen Wen; Chu, Pao Hsien; Wu, Chih Cheng; Hsu, Chih Hsin; Wen, Ming Shien; Voon, Wen Chol; Lin, Wei Shiang; Huang, Jin Long; Chen, Shyh Ming; Yang, Ning I.; Chang, Heng Chia; Chang, Kuan Cheng; Sung, Shih Hsien; Shyu, Kou Gi; Lin, Jiunn Lee; Mar, Guang Yuan; Chan, Kuei Chuan; Kuo, Jen Yuan; Wang, Ji Hung; Chen, Zhih Cherng; Tseng, Wei Kung; Cherng, Wen Jin.

In: Acta Cardiologica Sinica, Vol. 32, No. 4, 01.07.2016, p. 400-411.

Research output: Contribution to journalArticle

Wang, CC, Chang, HY, Yin, WH, Wu, YW, Chu, PH, Wu, CC, Hsu, CH, Wen, MS, Voon, WC, Lin, WS, Huang, JL, Chen, SM, Yang, NI, Chang, HC, Chang, KC, Sung, SH, Shyu, KG, Lin, JL, Mar, GY, Chan, KC, Kuo, JY, Wang, JH, Chen, ZC, Tseng, WK & Cherng, WJ 2016, 'TSOC-HFrEF registry: A registry of hospitalized patients with decompensated systolic heart failure: Description of population and management', Acta Cardiologica Sinica, vol. 32, no. 4, pp. 400-411. https://doi.org/10.6515/ACS20160704A
Wang, Chun Chieh ; Chang, Hung Yu ; Yin, Wei Hsian ; Wu, Yen Wen ; Chu, Pao Hsien ; Wu, Chih Cheng ; Hsu, Chih Hsin ; Wen, Ming Shien ; Voon, Wen Chol ; Lin, Wei Shiang ; Huang, Jin Long ; Chen, Shyh Ming ; Yang, Ning I. ; Chang, Heng Chia ; Chang, Kuan Cheng ; Sung, Shih Hsien ; Shyu, Kou Gi ; Lin, Jiunn Lee ; Mar, Guang Yuan ; Chan, Kuei Chuan ; Kuo, Jen Yuan ; Wang, Ji Hung ; Chen, Zhih Cherng ; Tseng, Wei Kung ; Cherng, Wen Jin. / TSOC-HFrEF registry : A registry of hospitalized patients with decompensated systolic heart failure: Description of population and management. In: Acta Cardiologica Sinica. 2016 ; Vol. 32, No. 4. pp. 400-411.
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abstract = "Introduction: Heart failure (HF) is a medical condition with a rapidly increasing incidence both in Taiwan and worldwide. The objective of the TSOC-HFrEF registry was to assess epidemiology, etiology, clinical management, and outcomes in a large sample of hospitalized patients presenting with acute decompensated systolic HF. Methods: The TSOC-HFrEF registry was a prospective, multicenter, observational survey of patients presenting to 21 medical centers or teaching hospitals in Taiwan. Hospitalized patients with either acute new-onset HF or acute decompensation of chronic HFrEF were enrolled. Data including demographic characteristics, medical history, primary etiology of HF, precipitating factors for HF hospitalization, presenting symptoms and signs, diagnostic and treatment procedures, in-hospital mortality, length of stay, and dischargemedications,were collected and analyzed. Results: A total of 1509 patients were enrolled into the registry by the end of October 2014, with a mean age of 64 years (72{\%} were male). Ischemic cardiomyopathy and dilated cardiomyopathy were diagnosed in 44{\%} and 33{\%} of patients, respectively. Coronary artery disease, hypertension, diabetes, and chronic renal insufficiency were the common comorbid conditions. Acute coronary syndrome, non-compliant to treatment, and concurrent infection were themajor precipitating factors for acute decompensation. The median length of hospital stay was 8 days, and the in-hospital mortality rate was 2.4{\%}. At discharge, 62{\%} of patients were prescribed either angiotensinconverting enzyme-inhibitors or angiotensin receptor blockers, 60{\%} were prescribed beta-blockers, and 49{\%} were prescribed mineralocorticoid receptor antagonists. Conclusions: The TSOC-HFrEF registry provided important insights into the current clinical characteristics and management of hospitalized decompensated systolic HF patients in Taiwan. One important observation was that adherence to guideline-directed medical therapy was suboptimal.",
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T1 - TSOC-HFrEF registry

T2 - A registry of hospitalized patients with decompensated systolic heart failure: Description of population and management

AU - Wang, Chun Chieh

AU - Chang, Hung Yu

AU - Yin, Wei Hsian

AU - Wu, Yen Wen

AU - Chu, Pao Hsien

AU - Wu, Chih Cheng

AU - Hsu, Chih Hsin

AU - Wen, Ming Shien

AU - Voon, Wen Chol

AU - Lin, Wei Shiang

AU - Huang, Jin Long

AU - Chen, Shyh Ming

AU - Yang, Ning I.

AU - Chang, Heng Chia

AU - Chang, Kuan Cheng

AU - Sung, Shih Hsien

AU - Shyu, Kou Gi

AU - Lin, Jiunn Lee

AU - Mar, Guang Yuan

AU - Chan, Kuei Chuan

AU - Kuo, Jen Yuan

AU - Wang, Ji Hung

AU - Chen, Zhih Cherng

AU - Tseng, Wei Kung

AU - Cherng, Wen Jin

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Introduction: Heart failure (HF) is a medical condition with a rapidly increasing incidence both in Taiwan and worldwide. The objective of the TSOC-HFrEF registry was to assess epidemiology, etiology, clinical management, and outcomes in a large sample of hospitalized patients presenting with acute decompensated systolic HF. Methods: The TSOC-HFrEF registry was a prospective, multicenter, observational survey of patients presenting to 21 medical centers or teaching hospitals in Taiwan. Hospitalized patients with either acute new-onset HF or acute decompensation of chronic HFrEF were enrolled. Data including demographic characteristics, medical history, primary etiology of HF, precipitating factors for HF hospitalization, presenting symptoms and signs, diagnostic and treatment procedures, in-hospital mortality, length of stay, and dischargemedications,were collected and analyzed. Results: A total of 1509 patients were enrolled into the registry by the end of October 2014, with a mean age of 64 years (72% were male). Ischemic cardiomyopathy and dilated cardiomyopathy were diagnosed in 44% and 33% of patients, respectively. Coronary artery disease, hypertension, diabetes, and chronic renal insufficiency were the common comorbid conditions. Acute coronary syndrome, non-compliant to treatment, and concurrent infection were themajor precipitating factors for acute decompensation. The median length of hospital stay was 8 days, and the in-hospital mortality rate was 2.4%. At discharge, 62% of patients were prescribed either angiotensinconverting enzyme-inhibitors or angiotensin receptor blockers, 60% were prescribed beta-blockers, and 49% were prescribed mineralocorticoid receptor antagonists. Conclusions: The TSOC-HFrEF registry provided important insights into the current clinical characteristics and management of hospitalized decompensated systolic HF patients in Taiwan. One important observation was that adherence to guideline-directed medical therapy was suboptimal.

AB - Introduction: Heart failure (HF) is a medical condition with a rapidly increasing incidence both in Taiwan and worldwide. The objective of the TSOC-HFrEF registry was to assess epidemiology, etiology, clinical management, and outcomes in a large sample of hospitalized patients presenting with acute decompensated systolic HF. Methods: The TSOC-HFrEF registry was a prospective, multicenter, observational survey of patients presenting to 21 medical centers or teaching hospitals in Taiwan. Hospitalized patients with either acute new-onset HF or acute decompensation of chronic HFrEF were enrolled. Data including demographic characteristics, medical history, primary etiology of HF, precipitating factors for HF hospitalization, presenting symptoms and signs, diagnostic and treatment procedures, in-hospital mortality, length of stay, and dischargemedications,were collected and analyzed. Results: A total of 1509 patients were enrolled into the registry by the end of October 2014, with a mean age of 64 years (72% were male). Ischemic cardiomyopathy and dilated cardiomyopathy were diagnosed in 44% and 33% of patients, respectively. Coronary artery disease, hypertension, diabetes, and chronic renal insufficiency were the common comorbid conditions. Acute coronary syndrome, non-compliant to treatment, and concurrent infection were themajor precipitating factors for acute decompensation. The median length of hospital stay was 8 days, and the in-hospital mortality rate was 2.4%. At discharge, 62% of patients were prescribed either angiotensinconverting enzyme-inhibitors or angiotensin receptor blockers, 60% were prescribed beta-blockers, and 49% were prescribed mineralocorticoid receptor antagonists. Conclusions: The TSOC-HFrEF registry provided important insights into the current clinical characteristics and management of hospitalized decompensated systolic HF patients in Taiwan. One important observation was that adherence to guideline-directed medical therapy was suboptimal.

KW - Beta-blocker

KW - Guideline

KW - Heart failure

KW - Renin-angiotensin system blocker

KW - Taiwan

KW - Treatment

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