Triple screening of gynecology cancers using cervical DNA methylation

Yu-Ping Laio, Po Hsuan Su, Rui-Lan Huang, Hui Chen Wang, Yu Chih Chen, Hung-Cheng Lai

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Abstract

Epigenetic changes play an important role in cancer development. Our previous research on the epigenomics of cervical cancer using genome-wide approaches identified 14 candidate genes that were hypermethylated in cervical cancer tissues. Most of these genes are transcription factors and development-related genes that are common in the development of various cancers. Recent researchers demonstrated that gene mutations in cervical scrapings can reflect the status of endometrial and ovarian cancer tissues.
Original languageTraditional Chinese
JournalInternational Journal of Gynecological Cancer
Publication statusPublished - 2015

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