Treatment Results of Laryngeal Cancer by Badiotherapy with or Without Surgery

雷 德, 陳 斯榮, 丁 禮莉(Lai-Lei Ting), 王 博民, 鍾 娜娜, 黃 昭源

Research output: Contribution to journalArticle

Abstract

Purpose: To evaluate the therapeutic results of laryngeal cancer patients treated at Department of Radiation Oncology of NTUII over the past ten years (1981-1990).Materials & Methods: One hundred and thirty-three laryngeal cancer patients treated at our clinic were analyzed clinically. All of them were squamous cell carcinoma. The age of the patients ranged from 34 to 84 years old with the highest incidence at the 60-69 age group. There were 128 male patients and 5 female patients with male to female ratio as 26:1. The numbers of patients in stage I to IV were 25, 21, 22, and 65, respectively. Stage IV patients accounted for about half of the cases. The numbers of supraglottic, glottic, and subglottic cancers were 51, 72, and 10, respectively. Glottic type accounted for more than half of the cases. Fifty-seven patients received primary radiotherapy. The other 76 patients received surgery before radiotherapy.Results: The overall actuarial five-year survival rate was 54.7%. The actuarial five-year survival rates for patients of stages Ⅰ, Ⅱ,Ⅲ and Ⅳ were 78.7%, 58.3%, 54%, and 44.4%, respectively. The five-year survival rates for supraglottic, glottic and subglottic cancers were 34.7%, 70.5%, and 38.9%, respectively.Conclusion: Recurrence after radiotherapy was salvaged by surgery satisfactorily in stages I and II, but the prognosis was poor for recurrent patients with initial stages III and IV. A life-long follow-up after radical radiotherapy is essential for early detection of recurrence and earlier salvage to improve the therapeutic result.
Original languageEnglish
Pages (from-to)21-32
Number of pages12
Journal放射治療與腫瘤學
Volume3
Issue number1
DOIs
Publication statusPublished - 1996
Externally publishedYes

Fingerprint

Laryngeal Neoplasms
Radiotherapy
Therapeutics
Tongue Neoplasms
Survival Rate
Recurrence
Radiation Oncology
Tongue
Squamous Cell Carcinoma
Age Groups

Keywords

  • 咽喉
  • 腫瘤
  • 放射治療
  • 救援手術
  • 五年存活率
  • Larynx
  • Neoplasm
  • Radiotherapy
  • Salvage operation
  • Five-year survival rate

Cite this

Treatment Results of Laryngeal Cancer by Badiotherapy with or Without Surgery. / 雷德; 陳斯榮; 丁禮莉(Lai-Lei Ting); 王博民; 鍾娜娜; 黃昭源.

In: 放射治療與腫瘤學, Vol. 3, No. 1, 1996, p. 21-32.

Research output: Contribution to journalArticle

雷德 ; 陳斯榮 ; 丁禮莉(Lai-Lei Ting) ; 王博民 ; 鍾娜娜 ; 黃昭源. / Treatment Results of Laryngeal Cancer by Badiotherapy with or Without Surgery. In: 放射治療與腫瘤學. 1996 ; Vol. 3, No. 1. pp. 21-32.
@article{528ceffd13f547a4b38e4a780e689c0b,
title = "Treatment Results of Laryngeal Cancer by Badiotherapy with or Without Surgery",
abstract = "Purpose: To evaluate the therapeutic results of laryngeal cancer patients treated at Department of Radiation Oncology of NTUII over the past ten years (1981-1990).Materials & Methods: One hundred and thirty-three laryngeal cancer patients treated at our clinic were analyzed clinically. All of them were squamous cell carcinoma. The age of the patients ranged from 34 to 84 years old with the highest incidence at the 60-69 age group. There were 128 male patients and 5 female patients with male to female ratio as 26:1. The numbers of patients in stage I to IV were 25, 21, 22, and 65, respectively. Stage IV patients accounted for about half of the cases. The numbers of supraglottic, glottic, and subglottic cancers were 51, 72, and 10, respectively. Glottic type accounted for more than half of the cases. Fifty-seven patients received primary radiotherapy. The other 76 patients received surgery before radiotherapy.Results: The overall actuarial five-year survival rate was 54.7{\%}. The actuarial five-year survival rates for patients of stages Ⅰ, Ⅱ,Ⅲ and Ⅳ were 78.7{\%}, 58.3{\%}, 54{\%}, and 44.4{\%}, respectively. The five-year survival rates for supraglottic, glottic and subglottic cancers were 34.7{\%}, 70.5{\%}, and 38.9{\%}, respectively.Conclusion: Recurrence after radiotherapy was salvaged by surgery satisfactorily in stages I and II, but the prognosis was poor for recurrent patients with initial stages III and IV. A life-long follow-up after radical radiotherapy is essential for early detection of recurrence and earlier salvage to improve the therapeutic result.",
keywords = "咽喉, 腫瘤, 放射治療, 救援手術, 五年存活率, Larynx, Neoplasm, Radiotherapy, Salvage operation, Five-year survival rate, Larynx, Neoplasm, Radiotherapy, Salvage operation, Five-year survival rate",
author = "德 雷 and 斯榮 陳 and 丁, {禮莉(Lai-Lei Ting)} and 博民 王 and 娜娜 鍾 and 昭源 黃",
year = "1996",
doi = "10.6316/TRO/199603",
language = "English",
volume = "3",
pages = "21--32",
journal = "放射治療與腫瘤學",
issn = "1023-988x",
publisher = "台灣放射腫瘤學會",
number = "1",

}

TY - JOUR

T1 - Treatment Results of Laryngeal Cancer by Badiotherapy with or Without Surgery

AU - 雷, 德

AU - 陳, 斯榮

AU - 丁, 禮莉(Lai-Lei Ting)

AU - 王, 博民

AU - 鍾, 娜娜

AU - 黃, 昭源

PY - 1996

Y1 - 1996

N2 - Purpose: To evaluate the therapeutic results of laryngeal cancer patients treated at Department of Radiation Oncology of NTUII over the past ten years (1981-1990).Materials & Methods: One hundred and thirty-three laryngeal cancer patients treated at our clinic were analyzed clinically. All of them were squamous cell carcinoma. The age of the patients ranged from 34 to 84 years old with the highest incidence at the 60-69 age group. There were 128 male patients and 5 female patients with male to female ratio as 26:1. The numbers of patients in stage I to IV were 25, 21, 22, and 65, respectively. Stage IV patients accounted for about half of the cases. The numbers of supraglottic, glottic, and subglottic cancers were 51, 72, and 10, respectively. Glottic type accounted for more than half of the cases. Fifty-seven patients received primary radiotherapy. The other 76 patients received surgery before radiotherapy.Results: The overall actuarial five-year survival rate was 54.7%. The actuarial five-year survival rates for patients of stages Ⅰ, Ⅱ,Ⅲ and Ⅳ were 78.7%, 58.3%, 54%, and 44.4%, respectively. The five-year survival rates for supraglottic, glottic and subglottic cancers were 34.7%, 70.5%, and 38.9%, respectively.Conclusion: Recurrence after radiotherapy was salvaged by surgery satisfactorily in stages I and II, but the prognosis was poor for recurrent patients with initial stages III and IV. A life-long follow-up after radical radiotherapy is essential for early detection of recurrence and earlier salvage to improve the therapeutic result.

AB - Purpose: To evaluate the therapeutic results of laryngeal cancer patients treated at Department of Radiation Oncology of NTUII over the past ten years (1981-1990).Materials & Methods: One hundred and thirty-three laryngeal cancer patients treated at our clinic were analyzed clinically. All of them were squamous cell carcinoma. The age of the patients ranged from 34 to 84 years old with the highest incidence at the 60-69 age group. There were 128 male patients and 5 female patients with male to female ratio as 26:1. The numbers of patients in stage I to IV were 25, 21, 22, and 65, respectively. Stage IV patients accounted for about half of the cases. The numbers of supraglottic, glottic, and subglottic cancers were 51, 72, and 10, respectively. Glottic type accounted for more than half of the cases. Fifty-seven patients received primary radiotherapy. The other 76 patients received surgery before radiotherapy.Results: The overall actuarial five-year survival rate was 54.7%. The actuarial five-year survival rates for patients of stages Ⅰ, Ⅱ,Ⅲ and Ⅳ were 78.7%, 58.3%, 54%, and 44.4%, respectively. The five-year survival rates for supraglottic, glottic and subglottic cancers were 34.7%, 70.5%, and 38.9%, respectively.Conclusion: Recurrence after radiotherapy was salvaged by surgery satisfactorily in stages I and II, but the prognosis was poor for recurrent patients with initial stages III and IV. A life-long follow-up after radical radiotherapy is essential for early detection of recurrence and earlier salvage to improve the therapeutic result.

KW - 咽喉

KW - 腫瘤

KW - 放射治療

KW - 救援手術

KW - 五年存活率

KW - Larynx

KW - Neoplasm

KW - Radiotherapy

KW - Salvage operation

KW - Five-year survival rate

KW - Larynx

KW - Neoplasm

KW - Radiotherapy

KW - Salvage operation

KW - Five-year survival rate

UR - http://www.airitilibrary.com/Publication/alDetailedMesh?DocID=1023988x-199603-3-1-21-32-a

U2 - 10.6316/TRO/199603

DO - 10.6316/TRO/199603

M3 - Article

VL - 3

SP - 21

EP - 32

JO - 放射治療與腫瘤學

JF - 放射治療與腫瘤學

SN - 1023-988x

IS - 1

ER -