Treatment of infected tibial nonunion with tobramycin-impregnated calcium sulfate

Report of two cases

Yao Hung Tsai, Tsung Jen Huang, Hsin Nung Shih, Robert Wen Wei Hsu

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The treatment of infected tibial nonunion usually includes a staged reconstruction protocol. We present 2 patients with tibial nonunion and plate loosening with oxacillin-resistant Staphylococcus aureus infection. The patients were treated using the removal of the plate, radical debridement, and implantation of gentamycin-impregnated cement beads during the first stage. During the second stage, plate fixation was performed and tobramycin-impregnated calcium sulfate (Osteoset T®) was used as a bone graft substitute. Neither an autogenous bone graft nor an allograft was used. At 3 years of follow-up, each tibia showed good union, and there was no recurrence of infection. We consider tobramycin-impregnated calcium sulfate to be an alternative method of bone grafting to treat infected tibial nonunion.

Original languageEnglish
Pages (from-to)542-547
Number of pages6
JournalChang Gung Medical Journal
Volume27
Issue number7
Publication statusPublished - Jul 2004
Externally publishedYes

Fingerprint

Calcium Sulfate
Tobramycin
Transplants
Bone Substitutes
Oxacillin
Bone Transplantation
Debridement
Infection
Gentamicins
Tibia
Allografts
Staphylococcus aureus
Bone and Bones
Recurrence
Therapeutics

Keywords

  • Osteomyelitis
  • Osteoset
  • Tibia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Treatment of infected tibial nonunion with tobramycin-impregnated calcium sulfate : Report of two cases. / Tsai, Yao Hung; Huang, Tsung Jen; Shih, Hsin Nung; Hsu, Robert Wen Wei.

In: Chang Gung Medical Journal, Vol. 27, No. 7, 07.2004, p. 542-547.

Research output: Contribution to journalArticle

Tsai, Yao Hung ; Huang, Tsung Jen ; Shih, Hsin Nung ; Hsu, Robert Wen Wei. / Treatment of infected tibial nonunion with tobramycin-impregnated calcium sulfate : Report of two cases. In: Chang Gung Medical Journal. 2004 ; Vol. 27, No. 7. pp. 542-547.
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