Toxoplasma gondii: seroprevalence and associated risk factors among preschool-aged children in Osun State, Nigeria

Oluyomi A. Sowemimo, Tsung Han Wu, Yueh Lun Lee, Samuel O. Asaolu, Ting Wu Chuang, Olaoluwa P. Akinwale, Bolaji O. Badejoko, Vincent P. Gyang, Timothy Nwafor, Emmanuel Henry, Chia Kwung Fan

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Abstract

Background: Toxoplasma gondii is an ubiquitous apicomplexan parasite, which causes toxoplasmosis in animals and humans worldwide. However, little is known about T. gondii infection among preschool-aged children in Nigeria. Methods: A cross-sectional study of 272 preschool children aged 2.25±1.09 years from four communities (Edunabon, Erin-Ijesha, Ijebu-jesa and Ile-Ife) in Osun State, Nigeria was conducted between January and July 2016, and the demographic data was obtained via questionnaires. Antibody titres against T. gondii of serum samples were assessed by ELISA. Results: The overall seroprevalence of T. gondii infection was 6.9% (19/272). There was no significant difference in seroprevalence of T. gondii infection between boys (7.04%; 10/142) and girls (6.92%; 9/130; p=0.97). No associations were found between age, gender, parental educational level, occupation and religion, and T. gondii seropositivity. None showed statistical significance between the risk factors tested after multivariate adjustment; nevertheless, residing in Ijebu-jesa community was shown to be associated with an increased risk of infection (p=0.04). Conclusion: This is the first report of T. gondii infection among preschool children in Nigeria. Prevalence studies such as this could help in the development of strategies for the future for disease prevention and control of T. gondii transmission.

Original languageEnglish
Pages (from-to)486-491
Number of pages6
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume112
Issue number11
DOIs
Publication statusPublished - Nov 1 2018

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ASJC Scopus subject areas

  • Parasitology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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