Toxoplasma gondii: seroprevalence and associated risk factors among preschool-aged children in Osun State, Nigeria

Oluyomi A. Sowemimo, Tsung Han Wu, Yueh Lun Lee, Samuel O. Asaolu, Ting Wu Chuang, Olaoluwa P. Akinwale, Bolaji O. Badejoko, Vincent P. Gyang, Timothy Nwafor, Emmanuel Henry, Chia Kwung Fan

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Toxoplasma gondii is an ubiquitous apicomplexan parasite, which causes toxoplasmosis in animals and humans worldwide. However, little is known about T. gondii infection among preschool-aged children in Nigeria. Methods: A cross-sectional study of 272 preschool children aged 2.25±1.09 years from four communities (Edunabon, Erin-Ijesha, Ijebu-jesa and Ile-Ife) in Osun State, Nigeria was conducted between January and July 2016, and the demographic data was obtained via questionnaires. Antibody titres against T. gondii of serum samples were assessed by ELISA. Results: The overall seroprevalence of T. gondii infection was 6.9% (19/272). There was no significant difference in seroprevalence of T. gondii infection between boys (7.04%; 10/142) and girls (6.92%; 9/130; p=0.97). No associations were found between age, gender, parental educational level, occupation and religion, and T. gondii seropositivity. None showed statistical significance between the risk factors tested after multivariate adjustment; nevertheless, residing in Ijebu-jesa community was shown to be associated with an increased risk of infection (p=0.04). Conclusion: This is the first report of T. gondii infection among preschool children in Nigeria. Prevalence studies such as this could help in the development of strategies for the future for disease prevention and control of T. gondii transmission.

Original languageEnglish
Pages (from-to)486-491
Number of pages6
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume112
Issue number11
DOIs
Publication statusPublished - Nov 1 2018

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Toxoplasmosis
Toxoplasma
Seroepidemiologic Studies
Preschool Children
Nigeria
Animal Toxoplasmosis
Cross-Sectional Studies
Social Adjustment
Religion
Occupations
Parasites
Parents
Enzyme-Linked Immunosorbent Assay
Demography
Antibodies
Infection
Serum

ASJC Scopus subject areas

  • Parasitology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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Toxoplasma gondii : seroprevalence and associated risk factors among preschool-aged children in Osun State, Nigeria. / Sowemimo, Oluyomi A.; Wu, Tsung Han; Lee, Yueh Lun; Asaolu, Samuel O.; Chuang, Ting Wu; Akinwale, Olaoluwa P.; Badejoko, Bolaji O.; Gyang, Vincent P.; Nwafor, Timothy; Henry, Emmanuel; Fan, Chia Kwung.

In: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 112, No. 11, 01.11.2018, p. 486-491.

Research output: Contribution to journalArticle

Sowemimo, Oluyomi A. ; Wu, Tsung Han ; Lee, Yueh Lun ; Asaolu, Samuel O. ; Chuang, Ting Wu ; Akinwale, Olaoluwa P. ; Badejoko, Bolaji O. ; Gyang, Vincent P. ; Nwafor, Timothy ; Henry, Emmanuel ; Fan, Chia Kwung. / Toxoplasma gondii : seroprevalence and associated risk factors among preschool-aged children in Osun State, Nigeria. In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 2018 ; Vol. 112, No. 11. pp. 486-491.
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AU - Asaolu, Samuel O.

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AU - Akinwale, Olaoluwa P.

AU - Badejoko, Bolaji O.

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AB - Background: Toxoplasma gondii is an ubiquitous apicomplexan parasite, which causes toxoplasmosis in animals and humans worldwide. However, little is known about T. gondii infection among preschool-aged children in Nigeria. Methods: A cross-sectional study of 272 preschool children aged 2.25±1.09 years from four communities (Edunabon, Erin-Ijesha, Ijebu-jesa and Ile-Ife) in Osun State, Nigeria was conducted between January and July 2016, and the demographic data was obtained via questionnaires. Antibody titres against T. gondii of serum samples were assessed by ELISA. Results: The overall seroprevalence of T. gondii infection was 6.9% (19/272). There was no significant difference in seroprevalence of T. gondii infection between boys (7.04%; 10/142) and girls (6.92%; 9/130; p=0.97). No associations were found between age, gender, parental educational level, occupation and religion, and T. gondii seropositivity. None showed statistical significance between the risk factors tested after multivariate adjustment; nevertheless, residing in Ijebu-jesa community was shown to be associated with an increased risk of infection (p=0.04). Conclusion: This is the first report of T. gondii infection among preschool children in Nigeria. Prevalence studies such as this could help in the development of strategies for the future for disease prevention and control of T. gondii transmission.

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