Thromboxane B2 transformed from arachidonic acid in carrageenin-induced granuloma

Wen Chang Chang, Sei itsu Murota, Susumu Tsurufuji

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Abstract

A main product (PI) transformed from arachidonic acid in carrageenin-induced granuloma in rats was structurally analysed. PI was converted to a more polar substance by the reduction with sodium borohydride. On the basis of the data on gas chromatography-mass spectrometry, its structure was identified with the hemiacetal derivative of 8-(1-hydroxy-3-oxopropyl)-9,12-heptadecadienoic acid (Thromboxane B2).

Original languageEnglish
Pages (from-to)17-24
Number of pages8
JournalProstaglandins
Volume13
Issue number1
DOIs
Publication statusPublished - 1977
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

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