Thromboxane B2 transformed from arachidonic acid in carrageenin-induced granuloma

Wen Chang Chang, Sei itsu Murota, Susumu Tsurufuji

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

A main product (PI) transformed from arachidonic acid in carrageenin-induced granuloma in rats was structurally analysed. PI was converted to a more polar substance by the reduction with sodium borohydride. On the basis of the data on gas chromatography-mass spectrometry, its structure was identified with the hemiacetal derivative of 8-(1-hydroxy-3-oxopropyl)-9,12-heptadecadienoic acid (Thromboxane B2).

Original languageEnglish
Pages (from-to)17-24
Number of pages8
JournalProstaglandins
Volume13
Issue number1
DOIs
Publication statusPublished - 1977
Externally publishedYes

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Thromboxane B2
Carrageenan
Granuloma
Arachidonic Acid
Gas chromatography
Gas Chromatography-Mass Spectrometry
Mass spectrometry
Rats
Derivatives
Acids
sodium borohydride

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

Cite this

Thromboxane B2 transformed from arachidonic acid in carrageenin-induced granuloma. / Chang, Wen Chang; Murota, Sei itsu; Tsurufuji, Susumu.

In: Prostaglandins, Vol. 13, No. 1, 1977, p. 17-24.

Research output: Contribution to journalArticle

Chang, Wen Chang ; Murota, Sei itsu ; Tsurufuji, Susumu. / Thromboxane B2 transformed from arachidonic acid in carrageenin-induced granuloma. In: Prostaglandins. 1977 ; Vol. 13, No. 1. pp. 17-24.
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