Thrombin mediates migration of rat brain astrocytes via PLC, Ca ²⁺, CaMKII, PKCα, and AP-1-dependent matrix metalloproteinase-9 expression

Medicine & Life Sciences

• 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester 22%
• 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione 21%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 27%
• 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole 35%
• Adenosine Triphosphatases 7%
• Astrocytes 72%
• bisindolylmaleimide I 11%
• Brain 38%
• Brain Injuries 7%
• Calcium Chelating Agents 11%
• Calcium-Calmodulin-Dependent Protein Kinase Type 2 100%
• Cell Movement 6%
• Encephalitis 8%
• Matrix Metalloproteinase 9 84%
• Messenger RNA 4%
• Mitogen-Activated Protein Kinase 1 17%
• Mitogen-Activated Protein Kinase 3 18%
• p38 Mitogen-Activated Protein Kinases 24%
• Pathologic Processes 8%
• phenylalanyl-prolyl-arginine chloromethyl ketone-thrombin 16%
• phosphatidylcholine-specific phospholipase C 13%
• Phosphorylation 10%
• pro-matrix metalloproteinase 9 13%
• pyrazolanthrone 31%
• Small Interfering RNA 6%
• tanshinone 11%
• Thapsigargin 19%
• Thrombin 77%
• Transcription Factor AP-1 87%
• Transfection 6%
• tricyclodecane-9-yl-xanthogenate 26%