The use of porcine small intestine submucosa implants might be associated with a high recurrence rate following laparoscopic herniorrhaphy

Chen-Hsun Ho, Pin-Wen Liao, Stephen Shei-Dei Yang, Fu-Shan Jaw, Yao-Chou Tsai

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BACKGROUND/PURPOSE: The efficacy of porcine small intestine submucosa (SIS) implants in hernia repair has rarely been reported and remained elusive. We herein report our experience to further elucidate the efficacy of SIS mesh in herniorrhaphy.

METHODS: Between June 2008 and October 2009, a total of 82 patients with 125 inguinal hernias undergoing endoscopic total extraperitoneal (TEP) herniorrhaphy were included. Seventy patients (with 108 hernias) had traditional polypropylene and 12 patients (with 17 hernias) had SIS mesh repair. Postoperative complications and recurrence rates were compared between the two meshes.

RESULTS: The demographics between two groups were similar. All operations were performed smoothly with laparoscopy, and the postoperative courses were uneventful. After a median follow-up of 18 months, five (7%) in the polypropylene group and three (25%) in the SIS group had chronic pain (p = 0.09). Five of 17 (29.4%) hernia repairs in the SIS group had an ipsilateral recurrence, compared to no recurrence in the polypropylene group. In the five cases, the second laparoscopy revealed the SIS mesh had been totally degraded and there was no obvious fibrotic tissue in the previous mesh sites.

CONCLUSION: Our data suggest that the use of SIS mesh in endoscopic TEP herniorrhaphy might be associated with a high recurrence rate. The second look laparoscopy in these recurrent cases revealed slow and inadequate integration of host tissue. More evidence is still required to further evaluate the efficacy of SIS mesh in endoscopic TEP herniorrhaphy.

Original languageEnglish
Pages (from-to)216-20
Number of pages5
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Issue number3
Publication statusPublished - Mar 2015
Externally publishedYes



  • Adult
  • Aged
  • Animals
  • Chi-Square Distribution
  • Female
  • Hernia, Inguinal
  • Herniorrhaphy
  • Humans
  • Intestinal Mucosa
  • Laparoscopy
  • Male
  • Middle Aged
  • Polypropylenes
  • Postoperative Complications
  • Randomized Controlled Trials as Topic
  • Recurrence
  • Retrospective Studies
  • Swine
  • Transplantation, Heterologous
  • Comparative Study
  • Journal Article

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