The use of porcine small intestine submucosa implants might be associated with a high recurrence rate following laparoscopic herniorrhaphy

Chen-Hsun Ho, Pin-Wen Liao, Stephen Shei-Dei Yang, Fu-Shan Jaw, Yao-Chou Tsai

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

BACKGROUND/PURPOSE: The efficacy of porcine small intestine submucosa (SIS) implants in hernia repair has rarely been reported and remained elusive. We herein report our experience to further elucidate the efficacy of SIS mesh in herniorrhaphy.

METHODS: Between June 2008 and October 2009, a total of 82 patients with 125 inguinal hernias undergoing endoscopic total extraperitoneal (TEP) herniorrhaphy were included. Seventy patients (with 108 hernias) had traditional polypropylene and 12 patients (with 17 hernias) had SIS mesh repair. Postoperative complications and recurrence rates were compared between the two meshes.

RESULTS: The demographics between two groups were similar. All operations were performed smoothly with laparoscopy, and the postoperative courses were uneventful. After a median follow-up of 18 months, five (7%) in the polypropylene group and three (25%) in the SIS group had chronic pain (p = 0.09). Five of 17 (29.4%) hernia repairs in the SIS group had an ipsilateral recurrence, compared to no recurrence in the polypropylene group. In the five cases, the second laparoscopy revealed the SIS mesh had been totally degraded and there was no obvious fibrotic tissue in the previous mesh sites.

CONCLUSION: Our data suggest that the use of SIS mesh in endoscopic TEP herniorrhaphy might be associated with a high recurrence rate. The second look laparoscopy in these recurrent cases revealed slow and inadequate integration of host tissue. More evidence is still required to further evaluate the efficacy of SIS mesh in endoscopic TEP herniorrhaphy.

Original languageEnglish
Pages (from-to)216-20
Number of pages5
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume114
Issue number3
DOIs
Publication statusPublished - Mar 2015
Externally publishedYes

Fingerprint

Herniorrhaphy
Small Intestine
Swine
Recurrence
Polypropylenes
Laparoscopy
Hernia
Inguinal Hernia
Chronic Pain
Demography

Keywords

  • Adult
  • Aged
  • Animals
  • Chi-Square Distribution
  • Female
  • Hernia, Inguinal
  • Herniorrhaphy
  • Humans
  • Intestinal Mucosa
  • Laparoscopy
  • Male
  • Middle Aged
  • Polypropylenes
  • Postoperative Complications
  • Randomized Controlled Trials as Topic
  • Recurrence
  • Retrospective Studies
  • Swine
  • Transplantation, Heterologous
  • Comparative Study
  • Journal Article

Cite this

The use of porcine small intestine submucosa implants might be associated with a high recurrence rate following laparoscopic herniorrhaphy. / Ho, Chen-Hsun; Liao, Pin-Wen; Yang, Stephen Shei-Dei; Jaw, Fu-Shan; Tsai, Yao-Chou.

In: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 114, No. 3, 03.2015, p. 216-20.

Research output: Contribution to journalArticle

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title = "The use of porcine small intestine submucosa implants might be associated with a high recurrence rate following laparoscopic herniorrhaphy",
abstract = "BACKGROUND/PURPOSE: The efficacy of porcine small intestine submucosa (SIS) implants in hernia repair has rarely been reported and remained elusive. We herein report our experience to further elucidate the efficacy of SIS mesh in herniorrhaphy.METHODS: Between June 2008 and October 2009, a total of 82 patients with 125 inguinal hernias undergoing endoscopic total extraperitoneal (TEP) herniorrhaphy were included. Seventy patients (with 108 hernias) had traditional polypropylene and 12 patients (with 17 hernias) had SIS mesh repair. Postoperative complications and recurrence rates were compared between the two meshes.RESULTS: The demographics between two groups were similar. All operations were performed smoothly with laparoscopy, and the postoperative courses were uneventful. After a median follow-up of 18 months, five (7{\%}) in the polypropylene group and three (25{\%}) in the SIS group had chronic pain (p = 0.09). Five of 17 (29.4{\%}) hernia repairs in the SIS group had an ipsilateral recurrence, compared to no recurrence in the polypropylene group. In the five cases, the second laparoscopy revealed the SIS mesh had been totally degraded and there was no obvious fibrotic tissue in the previous mesh sites.CONCLUSION: Our data suggest that the use of SIS mesh in endoscopic TEP herniorrhaphy might be associated with a high recurrence rate. The second look laparoscopy in these recurrent cases revealed slow and inadequate integration of host tissue. More evidence is still required to further evaluate the efficacy of SIS mesh in endoscopic TEP herniorrhaphy.",
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author = "Chen-Hsun Ho and Pin-Wen Liao and Yang, {Stephen Shei-Dei} and Fu-Shan Jaw and Yao-Chou Tsai",
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TY - JOUR

T1 - The use of porcine small intestine submucosa implants might be associated with a high recurrence rate following laparoscopic herniorrhaphy

AU - Ho, Chen-Hsun

AU - Liao, Pin-Wen

AU - Yang, Stephen Shei-Dei

AU - Jaw, Fu-Shan

AU - Tsai, Yao-Chou

N1 - Copyright © 2013. Published by Elsevier B.V.

PY - 2015/3

Y1 - 2015/3

N2 - BACKGROUND/PURPOSE: The efficacy of porcine small intestine submucosa (SIS) implants in hernia repair has rarely been reported and remained elusive. We herein report our experience to further elucidate the efficacy of SIS mesh in herniorrhaphy.METHODS: Between June 2008 and October 2009, a total of 82 patients with 125 inguinal hernias undergoing endoscopic total extraperitoneal (TEP) herniorrhaphy were included. Seventy patients (with 108 hernias) had traditional polypropylene and 12 patients (with 17 hernias) had SIS mesh repair. Postoperative complications and recurrence rates were compared between the two meshes.RESULTS: The demographics between two groups were similar. All operations were performed smoothly with laparoscopy, and the postoperative courses were uneventful. After a median follow-up of 18 months, five (7%) in the polypropylene group and three (25%) in the SIS group had chronic pain (p = 0.09). Five of 17 (29.4%) hernia repairs in the SIS group had an ipsilateral recurrence, compared to no recurrence in the polypropylene group. In the five cases, the second laparoscopy revealed the SIS mesh had been totally degraded and there was no obvious fibrotic tissue in the previous mesh sites.CONCLUSION: Our data suggest that the use of SIS mesh in endoscopic TEP herniorrhaphy might be associated with a high recurrence rate. The second look laparoscopy in these recurrent cases revealed slow and inadequate integration of host tissue. More evidence is still required to further evaluate the efficacy of SIS mesh in endoscopic TEP herniorrhaphy.

AB - BACKGROUND/PURPOSE: The efficacy of porcine small intestine submucosa (SIS) implants in hernia repair has rarely been reported and remained elusive. We herein report our experience to further elucidate the efficacy of SIS mesh in herniorrhaphy.METHODS: Between June 2008 and October 2009, a total of 82 patients with 125 inguinal hernias undergoing endoscopic total extraperitoneal (TEP) herniorrhaphy were included. Seventy patients (with 108 hernias) had traditional polypropylene and 12 patients (with 17 hernias) had SIS mesh repair. Postoperative complications and recurrence rates were compared between the two meshes.RESULTS: The demographics between two groups were similar. All operations were performed smoothly with laparoscopy, and the postoperative courses were uneventful. After a median follow-up of 18 months, five (7%) in the polypropylene group and three (25%) in the SIS group had chronic pain (p = 0.09). Five of 17 (29.4%) hernia repairs in the SIS group had an ipsilateral recurrence, compared to no recurrence in the polypropylene group. In the five cases, the second laparoscopy revealed the SIS mesh had been totally degraded and there was no obvious fibrotic tissue in the previous mesh sites.CONCLUSION: Our data suggest that the use of SIS mesh in endoscopic TEP herniorrhaphy might be associated with a high recurrence rate. The second look laparoscopy in these recurrent cases revealed slow and inadequate integration of host tissue. More evidence is still required to further evaluate the efficacy of SIS mesh in endoscopic TEP herniorrhaphy.

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KW - Aged

KW - Animals

KW - Chi-Square Distribution

KW - Female

KW - Hernia, Inguinal

KW - Herniorrhaphy

KW - Humans

KW - Intestinal Mucosa

KW - Laparoscopy

KW - Male

KW - Middle Aged

KW - Polypropylenes

KW - Postoperative Complications

KW - Randomized Controlled Trials as Topic

KW - Recurrence

KW - Retrospective Studies

KW - Swine

KW - Transplantation, Heterologous

KW - Comparative Study

KW - Journal Article

U2 - 10.1016/j.jfma.2013.03.007

DO - 10.1016/j.jfma.2013.03.007

M3 - Article

C2 - 23725634

VL - 114

SP - 216

EP - 220

JO - Journal of the Formosan Medical Association

JF - Journal of the Formosan Medical Association

SN - 0929-6646

IS - 3

ER -