The significance of body weight change in non-Hodgkins lymphoma

Yung Hsin Chin, Jacqueline Ming Liu, John Jen Tai, Mei Shing Chuang, Yueh Ling Ho, Yuh Min Chen, Jacqueline Whang-Peng, Ann Lii Cheng

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: The purpose of this study was to evaluate the effect of weight changes after completion of chemotherapy on the prognosis and survival of patients with intermediate and high grade non-Hodgkin's lymphoma. Materials and Methods: A retrospective analysis of data on patients from the TCOG T1488 protocol, a phase II study using CHOP in the treatment of intermediate and high grade lymphoma. From September, 1988 to December 1994, 138 adult patients had complete weight data for analysis. Weight gain in lymphoma patients after therapy significantly correlated with improved survival (Logrank test p =. 0031). In patients with initial B symptoms, weight gain after therapy correlated with survival (Logrank test p=. 0039), female patients (odds ratio = 6.2) were less likely to gain weight on treatment. Conclusion: Weight gain after chemotherapy for lymphoma is a significant positive prognostic factor for survival.

Original languageEnglish
Pages (from-to)5607-5610
Number of pages4
JournalAnticancer Research
Volume19
Issue number6 C
Publication statusPublished - Dec 1 1999
Externally publishedYes

Keywords

  • B symptoms
  • Lymphoma
  • Response
  • Survival
  • Weight changes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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  • Cite this

    Chin, Y. H., Liu, J. M., Tai, J. J., Chuang, M. S., Ho, Y. L., Chen, Y. M., Whang-Peng, J., & Cheng, A. L. (1999). The significance of body weight change in non-Hodgkins lymphoma. Anticancer Research, 19(6 C), 5607-5610.