The Role of High Sensitivity C-Reactive Protein and Coronary Artery Calcium as Predictors of the Long-term Prognosis in Men with Coronary Artery Disease

Zhong Xuan Ye, Po Hsun Huang, Hsin Bang Leu, Tao Cheng Wu, Shing Jong Lin, Jaw Wen Chen

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Measurements of coronary artery calcium (CAC) and of high sensitivity C-reactive protein (hsCRP) are used to predict the risk of cardiovascular events in patients with coronary artery disease (CAD). The aim of our study was to investigate the hypothesis that combining the hsCRP level and CAC score can increase the predictive value of these parameters for future cardiovascular events in male patients with suspected CAD. Methods: We included 90 male patients with stable angina. We measured their serum hsCRP and CAC scores by using electron-beam computerized tomography. These baseline parameters were correlated to the clinical cardiovascular events within the follow-up period. Results: During the follow-up period of up to 50 months (median 27 months), 13 major cardiovascular events were recorded. In multivariate regression analysis, after being adjusted for conventional risk factors, hsCRP and CAC score, hsCRP level was the only independent predictor of cardiovascular events. Further analysis was performed among the four groups classified by CAC score (CAC score ≥100 or

Original languageEnglish
Pages (from-to)39-42
Number of pages4
JournalJournal of Experimental and Clinical Medicine(Taiwan)
Volume4
Issue number1
DOIs
Publication statusPublished - Feb 2012

Keywords

  • Atherosclerosis
  • Coronary artery calcium
  • Coronary artery disease
  • High sensitivity C-reactive protein
  • Male sex

ASJC Scopus subject areas

  • Medicine(all)

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