The risk of temporomandibular disorder in patients with depression: A population-based cohort study

Chun Hui Liao, Chen Shu Chang, Shih Ni Chang, Hsien Yuan Lane, Shu Yu Lyu, Donald E. Morisky, Fung Chang Sung

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Abstract

Objectives: This study used a population-based retrospective cohort design to examine whether depression is a risk factor of temporomandibular disorder (TMD) Methods: From a universal insurance database, we identified 7587 patients who are newly diagnosed individuals with depression in 2000 and 2001. A total of 30 197 comparison subjects were randomly selected from a nondepression cohort. Both groups were followed until the end of 2008 to measure the incidence of TMD. Results: The incidence of TMD was 2.65 times higher in the depression cohort than in the nondepression cohort (6.16 versus 2.32 per 1000 person-years). The hazard ratio (HR) measured by multivariate Cox's proportional hazard regression analysis of TMD for the depression cohort was 2.21 (95% confidence interval (CI) 1.83-2.66), after controlling for socio-demographic factors and other psychiatric comorbidities. Women had higher risk to develop TMD than men (HR 1.61, 95% CI 1.36-1.92 for women without depression; HR 3.54, 95% CI 2.81-4.45 for women with depression). Conclusions: This study demonstrates that patients with depression are at an elevated risk of developing TMD.

Original languageEnglish
Pages (from-to)525-531
Number of pages7
JournalCommunity Dentistry and Oral Epidemiology
Volume39
Issue number6
DOIs
Publication statusPublished - Dec 2011

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Temporomandibular Joint Disorders
Cohort Studies
Population
Confidence Intervals
Incidence
Insurance
Psychiatry
Comorbidity
Regression Analysis
Demography
Databases

Keywords

  • depression
  • hazard ratio
  • population-based study
  • retrospective cohort design
  • temporomandibular disorder

ASJC Scopus subject areas

  • Dentistry(all)
  • Public Health, Environmental and Occupational Health

Cite this

The risk of temporomandibular disorder in patients with depression : A population-based cohort study. / Liao, Chun Hui; Chang, Chen Shu; Chang, Shih Ni; Lane, Hsien Yuan; Lyu, Shu Yu; Morisky, Donald E.; Sung, Fung Chang.

In: Community Dentistry and Oral Epidemiology, Vol. 39, No. 6, 12.2011, p. 525-531.

Research output: Contribution to journalArticle

Liao, Chun Hui ; Chang, Chen Shu ; Chang, Shih Ni ; Lane, Hsien Yuan ; Lyu, Shu Yu ; Morisky, Donald E. ; Sung, Fung Chang. / The risk of temporomandibular disorder in patients with depression : A population-based cohort study. In: Community Dentistry and Oral Epidemiology. 2011 ; Vol. 39, No. 6. pp. 525-531.
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