Abstract

Background Articles in the literature describing the association between body composition and osteoporosis in subjects with poliomyelitis are scarce. Objective To assess the relationship between body composition and femoral neck osteoporosis or osteopenia in adults with previous polio. Method After excluding postmenopausal women, 44 polio (mean age ± standard deviation, 46.1 ± 3.3 years) and 44 able-bodied control volunteers (47.0 ± 4.0 years) participated in the study. Each participant's femoral neck bone mineral density (FNBMD) and whole body composition were measured using dual-energy X-ray absorptiometry. With local reference BMD values of normal young adults installed in the instrument, we obtained T-score values that depended on each FNBMD value. A T-score value of ≤-1.0 indicated decreased T-score, including osteoporosis (T-score ≤ -2.5) and osteopenia (-1.0 to -2.5). This study conducted logistic regression analyses to find factors associated with osteoporosis and osteopenia. Results Based on the FNBMD T-score values, 60.0% of middle-aged men with polio had osteoporosis. In adjusted logistic regression analyses, total lean tissue mass (Adjusted odds ratio [95% confidence interval], 0.74 [0.56-0.99], P <0.05) and male gender (947.16 [6.02-148,926.16], P <0.01) were important factors associated with decreased T-score in polio group. Conclusions Osteoporosis or osteopenia is a common medical problem for middle-aged men with polio. Reduced total lean tissue mass seems to be one of the important factors associated with osteoporosis or osteopenia among subjects with polio. Further research for a clinical tool to assess lean tissue mass for subjects with polio is needed.

Original languageEnglish
Pages (from-to)284-289
Number of pages6
JournalDisability and Health Journal
Volume8
Issue number2
DOIs
Publication statusPublished - Apr 1 2015

Fingerprint

Metabolic Bone Diseases
Femur Neck
Poliomyelitis
Body Composition
Osteoporosis
Bone Density
Logistic Models
Regression Analysis
Photon Absorptiometry
Young Adult
Volunteers
Reference Values
Odds Ratio
Confidence Intervals
Research

Keywords

  • Body composition
  • Femoral neck
  • Osteoporosis
  • Poliomyelitis

ASJC Scopus subject areas

  • Medicine(all)
  • Public Health, Environmental and Occupational Health

Cite this

@article{276aad052a974045b62d41e566e20478,
title = "The relationship between body composition and femoral neck osteoporosis or osteopenia in adults with previous poliomyelitis",
abstract = "Background Articles in the literature describing the association between body composition and osteoporosis in subjects with poliomyelitis are scarce. Objective To assess the relationship between body composition and femoral neck osteoporosis or osteopenia in adults with previous polio. Method After excluding postmenopausal women, 44 polio (mean age ± standard deviation, 46.1 ± 3.3 years) and 44 able-bodied control volunteers (47.0 ± 4.0 years) participated in the study. Each participant's femoral neck bone mineral density (FNBMD) and whole body composition were measured using dual-energy X-ray absorptiometry. With local reference BMD values of normal young adults installed in the instrument, we obtained T-score values that depended on each FNBMD value. A T-score value of ≤-1.0 indicated decreased T-score, including osteoporosis (T-score ≤ -2.5) and osteopenia (-1.0 to -2.5). This study conducted logistic regression analyses to find factors associated with osteoporosis and osteopenia. Results Based on the FNBMD T-score values, 60.0{\%} of middle-aged men with polio had osteoporosis. In adjusted logistic regression analyses, total lean tissue mass (Adjusted odds ratio [95{\%} confidence interval], 0.74 [0.56-0.99], P <0.05) and male gender (947.16 [6.02-148,926.16], P <0.01) were important factors associated with decreased T-score in polio group. Conclusions Osteoporosis or osteopenia is a common medical problem for middle-aged men with polio. Reduced total lean tissue mass seems to be one of the important factors associated with osteoporosis or osteopenia among subjects with polio. Further research for a clinical tool to assess lean tissue mass for subjects with polio is needed.",
keywords = "Body composition, Femoral neck, Osteoporosis, Poliomyelitis",
author = "Kwang-hwa Chang and Sung-Hui Tseng and Lin, {Yu Ching} and Chien-Hung Lai and Hsiao, {Wen Tien} and Shih-Ching Chen",
year = "2015",
month = "4",
day = "1",
doi = "10.1016/j.dhjo.2014.09.011",
language = "English",
volume = "8",
pages = "284--289",
journal = "Disability and Health Journal",
issn = "1936-6574",
publisher = "Elsevier Inc.",
number = "2",

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TY - JOUR

T1 - The relationship between body composition and femoral neck osteoporosis or osteopenia in adults with previous poliomyelitis

AU - Chang, Kwang-hwa

AU - Tseng, Sung-Hui

AU - Lin, Yu Ching

AU - Lai, Chien-Hung

AU - Hsiao, Wen Tien

AU - Chen, Shih-Ching

PY - 2015/4/1

Y1 - 2015/4/1

N2 - Background Articles in the literature describing the association between body composition and osteoporosis in subjects with poliomyelitis are scarce. Objective To assess the relationship between body composition and femoral neck osteoporosis or osteopenia in adults with previous polio. Method After excluding postmenopausal women, 44 polio (mean age ± standard deviation, 46.1 ± 3.3 years) and 44 able-bodied control volunteers (47.0 ± 4.0 years) participated in the study. Each participant's femoral neck bone mineral density (FNBMD) and whole body composition were measured using dual-energy X-ray absorptiometry. With local reference BMD values of normal young adults installed in the instrument, we obtained T-score values that depended on each FNBMD value. A T-score value of ≤-1.0 indicated decreased T-score, including osteoporosis (T-score ≤ -2.5) and osteopenia (-1.0 to -2.5). This study conducted logistic regression analyses to find factors associated with osteoporosis and osteopenia. Results Based on the FNBMD T-score values, 60.0% of middle-aged men with polio had osteoporosis. In adjusted logistic regression analyses, total lean tissue mass (Adjusted odds ratio [95% confidence interval], 0.74 [0.56-0.99], P <0.05) and male gender (947.16 [6.02-148,926.16], P <0.01) were important factors associated with decreased T-score in polio group. Conclusions Osteoporosis or osteopenia is a common medical problem for middle-aged men with polio. Reduced total lean tissue mass seems to be one of the important factors associated with osteoporosis or osteopenia among subjects with polio. Further research for a clinical tool to assess lean tissue mass for subjects with polio is needed.

AB - Background Articles in the literature describing the association between body composition and osteoporosis in subjects with poliomyelitis are scarce. Objective To assess the relationship between body composition and femoral neck osteoporosis or osteopenia in adults with previous polio. Method After excluding postmenopausal women, 44 polio (mean age ± standard deviation, 46.1 ± 3.3 years) and 44 able-bodied control volunteers (47.0 ± 4.0 years) participated in the study. Each participant's femoral neck bone mineral density (FNBMD) and whole body composition were measured using dual-energy X-ray absorptiometry. With local reference BMD values of normal young adults installed in the instrument, we obtained T-score values that depended on each FNBMD value. A T-score value of ≤-1.0 indicated decreased T-score, including osteoporosis (T-score ≤ -2.5) and osteopenia (-1.0 to -2.5). This study conducted logistic regression analyses to find factors associated with osteoporosis and osteopenia. Results Based on the FNBMD T-score values, 60.0% of middle-aged men with polio had osteoporosis. In adjusted logistic regression analyses, total lean tissue mass (Adjusted odds ratio [95% confidence interval], 0.74 [0.56-0.99], P <0.05) and male gender (947.16 [6.02-148,926.16], P <0.01) were important factors associated with decreased T-score in polio group. Conclusions Osteoporosis or osteopenia is a common medical problem for middle-aged men with polio. Reduced total lean tissue mass seems to be one of the important factors associated with osteoporosis or osteopenia among subjects with polio. Further research for a clinical tool to assess lean tissue mass for subjects with polio is needed.

KW - Body composition

KW - Femoral neck

KW - Osteoporosis

KW - Poliomyelitis

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U2 - 10.1016/j.dhjo.2014.09.011

DO - 10.1016/j.dhjo.2014.09.011

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JO - Disability and Health Journal

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