疑似罹患冠狀動脈疾病中年女性高敏感度C-反應蛋白影響因素之探討

Translated title of the contribution: The Related Factors of High-Sensitivity C-Reactive Protein in Middle-Aged Women with Suspected Coronary Artery Disease

蔡青青, 謝敏雄, 王烱中, 楊弘宇, 鄭綺

Research output: Contribution to journalArticle

Abstract

Background: High-sensitivity C-reactive protein (hsCRP) is a key risk factor in coronary artery disease (CAD) in women; however, previous studies yielded inconsistent results regarding the influencing factors that affect women. Purpose:The purpose of this study was to explore the related factors of hsCRP in middle-aged women who were suspected of having CAD. Methods:This was a cross-sectional study, and 128 middle-aged women who were suspected of having CAD and were waiting for catheterization were recruited. Blood was collected to conduct analyses during catheterization procedures. Patients were divided into 2 groups based on their hsCRP blood levels (≤ 3or > 3 mg/L). Data were collected from completed questionnaires, medical records, and blood test results. Results: Overall, the average age was 56.9±5.7 years, and 23 (18%) exhibited an hsCRP level of > 3 mg/L. Patients who were classified into the hsCRP level of > 3 mg/L group had a history of renal insufficiency, had used diuretics, possessed a high number of stenotic blood vessels, and were physically inactive. After controlling confounding factors, physical inactivity was a significant predictor to the hsCRP level. Patients who were physical inactivity possessed a 3.8-fold higher probability of exhibiting higher hsCRP levels than patients who were active (P = 0.01). Conclusions:Physical inactivity was significantly correlated with high hsCRP levels. Middle-aged women should maintain physical activity to reduce inflammatory reactions, thereby reducing the risk of CAD.
Original languageTraditional Chinese
Pages (from-to)11-23
Number of pages13
Journal新臺北護理期刊
Volume17
Issue number2
DOIs
Publication statusPublished - Sep 2015

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C-Reactive Protein
Coronary Artery Disease
Catheterization
Hematologic Tests
Diuretics
Medical Records
Renal Insufficiency
Blood Vessels
Cross-Sectional Studies
Exercise

Keywords

  • High sensitivity C-reactive protein
  • Women
  • Middle aged
  • Physical activity

Cite this

疑似罹患冠狀動脈疾病中年女性高敏感度C-反應蛋白影響因素之探討. / 蔡青青; 謝敏雄; 王烱中; 楊弘宇; 鄭綺.

In: 新臺北護理期刊, Vol. 17, No. 2, 09.2015, p. 11-23.

Research output: Contribution to journalArticle

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title = "疑似罹患冠狀動脈疾病中年女性高敏感度C-反應蛋白影響因素之探討",
abstract = "背景:高敏感度C-反應蛋白(high-sensitivity C-reactive protein, hsCRP)是女性罹患冠狀動脈疾病(coronary arterydisease, CAD)重要的危險因素,就女性而言,其影響因素之先前研究結果並不一致。目的:本研究目的在探討疑似罹患CAD中年女性影響hsCRP值之相關因素。方法:採橫斷式研究,選取128位疑似CAD等待心導管檢查中年女性,於心導管室進行檢查前抽取血液進行分析,依照hsCRP血中濃度分為兩組(≦3、>3mg/L)。以填寫問卷、查閱病歷、血液檢驗方式收集資料。結果: 整體平均56.9±5.7歲,23位(18{\%})病患hsCRP血中濃度>3 mg/L。hsCRP>3 mg/L組較多病患有腎功能不全病史、使用利尿劑、血管狹窄數目多、身體不活動情形。控制干擾因素後,身體不活動是hsCRP有意義的預測因子。身體不活動者發生高hsCRP的機率是有活動者的3.8倍(P=0.01)。結論:身體不活動與高hsCRP有顯著相關性,中年女性應維持身體活動以減輕炎症反應,進而防治CAD。",
keywords = "高敏感度C-反應蛋白, 女性, 中年, 身體活動, High sensitivity C-reactive protein, Women, Middle aged, Physical activity",
author = "蔡青青 and 謝敏雄 and 王烱中 and 楊弘宇 and 鄭綺",
year = "2015",
month = "9",
doi = "10.6540/NTJN.2015.2.002",
language = "繁體中文",
volume = "17",
pages = "11--23",
journal = "新臺北護理期刊",
issn = "1563-1230",
publisher = "臺北醫學大學護理學院",
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AU - 蔡青青, null

AU - 謝敏雄, null

AU - 王烱中, null

AU - 楊弘宇, null

AU - 鄭綺, null

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N2 - 背景:高敏感度C-反應蛋白(high-sensitivity C-reactive protein, hsCRP)是女性罹患冠狀動脈疾病(coronary arterydisease, CAD)重要的危險因素,就女性而言,其影響因素之先前研究結果並不一致。目的:本研究目的在探討疑似罹患CAD中年女性影響hsCRP值之相關因素。方法:採橫斷式研究,選取128位疑似CAD等待心導管檢查中年女性,於心導管室進行檢查前抽取血液進行分析,依照hsCRP血中濃度分為兩組(≦3、>3mg/L)。以填寫問卷、查閱病歷、血液檢驗方式收集資料。結果: 整體平均56.9±5.7歲,23位(18%)病患hsCRP血中濃度>3 mg/L。hsCRP>3 mg/L組較多病患有腎功能不全病史、使用利尿劑、血管狹窄數目多、身體不活動情形。控制干擾因素後,身體不活動是hsCRP有意義的預測因子。身體不活動者發生高hsCRP的機率是有活動者的3.8倍(P=0.01)。結論:身體不活動與高hsCRP有顯著相關性,中年女性應維持身體活動以減輕炎症反應,進而防治CAD。

AB - 背景:高敏感度C-反應蛋白(high-sensitivity C-reactive protein, hsCRP)是女性罹患冠狀動脈疾病(coronary arterydisease, CAD)重要的危險因素,就女性而言,其影響因素之先前研究結果並不一致。目的:本研究目的在探討疑似罹患CAD中年女性影響hsCRP值之相關因素。方法:採橫斷式研究,選取128位疑似CAD等待心導管檢查中年女性,於心導管室進行檢查前抽取血液進行分析,依照hsCRP血中濃度分為兩組(≦3、>3mg/L)。以填寫問卷、查閱病歷、血液檢驗方式收集資料。結果: 整體平均56.9±5.7歲,23位(18%)病患hsCRP血中濃度>3 mg/L。hsCRP>3 mg/L組較多病患有腎功能不全病史、使用利尿劑、血管狹窄數目多、身體不活動情形。控制干擾因素後,身體不活動是hsCRP有意義的預測因子。身體不活動者發生高hsCRP的機率是有活動者的3.8倍(P=0.01)。結論:身體不活動與高hsCRP有顯著相關性,中年女性應維持身體活動以減輕炎症反應,進而防治CAD。

KW - 高敏感度C-反應蛋白

KW - 女性

KW - 中年

KW - 身體活動

KW - High sensitivity C-reactive protein

KW - Women

KW - Middle aged

KW - Physical activity

U2 - 10.6540/NTJN.2015.2.002

DO - 10.6540/NTJN.2015.2.002

M3 - 文章

VL - 17

SP - 11

EP - 23

JO - 新臺北護理期刊

JF - 新臺北護理期刊

SN - 1563-1230

IS - 2

ER -