The prognostic significance of pathologic characteristics of breast cancer patients in Taiwan

J. S. Chu, C. Huang, K. J. Chang

Research output: Contribution to journalArticle

Abstract

To investigate the prognostic significance of pathologic characteristics of breast cancer patients, we retrospectively studied 514 patients with operable cancer from 1978 through 1987. The mean age of the patients was 50.2 ± 12.4 years. Tumor sizes ranged from 0.7 to 13.0 cm, with a mean size of 4.26 ± 2.4 cm. Axillary node metastases were found in 56.4% of the patients. Univariate analysis on the survival rate revealed that the number of positive nodes, tumor size, lymphatic permeation, tumor necrosis, histologic type, histologic grade, and age were significant prognostic factors. Multivariate Cox regression analysis showed that the number of positive nodes (p <0.00005), histologic grade (p = 0.0002), and tumor size (p = 0.0108) were independent prognostic factors. Our study confirms the importance of pathologic characteristics in predicting the prognosis of breast cancer patients.

Original languageEnglish
Pages (from-to)265-271
Number of pages7
JournalTzu Chi Medical Journal
Volume10
Issue number4
Publication statusPublished - 1998

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Taiwan
Breast Neoplasms
Neoplasms
Necrosis
Survival Rate
Regression Analysis
Neoplasm Metastasis

Keywords

  • Breast cancer
  • Pathology
  • Prognosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The prognostic significance of pathologic characteristics of breast cancer patients in Taiwan. / Chu, J. S.; Huang, C.; Chang, K. J.

In: Tzu Chi Medical Journal, Vol. 10, No. 4, 1998, p. 265-271.

Research output: Contribution to journalArticle

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