This case report described the nursing experience of a first-time mother who gave birth to an infant with hyperbilirubinemia undergoing phototherapy and her family members. As a consequence of hospitalization for phototherapy, the woman interrupted the process of breastfeeding.Based on the Gorden's eleven-functional health pattern assessments, health problems including acute pain, anxiety and interrupted breastfeeding were identified through observation, physical assessment and interviews. In view of the above-mentioned health problems, the author provided direct nursing care to relieve acute pain, such as providing information about breastfeeding of hyperbilirubinemia infants, sharing experience, and giving support. At the same time, the primary nurse assisted the father to share the responsibility of maternal and newborn care to strengthen the role of being a fatherhood. The results of the nursing care helped the mother and her family overcome the physical and psychological barriers, and successfully breastfeed their baby.In this case report, the author shared positive experiences in helping the mother who was willing to breastfeed her hyperbilirubinemia infant. Caring, emotional support, teaching and providing bedside assistance as soon as possible could be key elements of successful breastfeeding.