The management of papillary lesion of the breast by core needle biopsy

H. S. Tseng, Y. L. Chen, S. T. Chen, Y. C. Wu, S. J. Kuo, L. S. Chen, H. K. Wu, D. R. Chen

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Background: The purpose of this study was to determine the accuracy of core needle biopsy (CNB) diagnoses of papillary breast lesions, and to identify the risk factors and histologic features, compared with excisional biopsy (EB). Method: We retrospectively reviewed 1682 sonographically guided core needle biopsies performed at one single medical center from January 2001 through December 2005, and identified 41 papillary lesions. Surgical correlation was available for 35 cases, 2 cases were loss follow-up and 4 cases diagnosed as papilloma by core needle biopsy were followed up with imaging for at least 24 months. Results: The pathologic diagnoses for the 35 papillary lesions obtained at core biopsy were benign in 24 cases, atypical in 7, and malignant in 4. Of those diagnosed as benign lesions at CNB, 7/24 turned out to be malignant. In the hyperplasia group, 5/7 were malignant. The total upgrade rate was 39%. The positive predict value was 100% and negative predict value was 61%. Conclusion: All papillary lesions of the breast diagnosed by CNB should be excised because a substantial number of lesions were upgraded of diagnoses at excision.

Original languageEnglish
Pages (from-to)21-24
Number of pages4
JournalEuropean Journal of Surgical Oncology
Volume35
Issue number1
DOIs
Publication statusPublished - Jan 2009
Externally publishedYes

Fingerprint

Large-Core Needle Biopsy
Breast
Biopsy
Papilloma
Hyperplasia

Keywords

  • Core needle biopsy
  • Papillary lesion

ASJC Scopus subject areas

  • Oncology
  • Surgery

Cite this

The management of papillary lesion of the breast by core needle biopsy. / Tseng, H. S.; Chen, Y. L.; Chen, S. T.; Wu, Y. C.; Kuo, S. J.; Chen, L. S.; Wu, H. K.; Chen, D. R.

In: European Journal of Surgical Oncology, Vol. 35, No. 1, 01.2009, p. 21-24.

Research output: Contribution to journalArticle

Tseng, H. S. ; Chen, Y. L. ; Chen, S. T. ; Wu, Y. C. ; Kuo, S. J. ; Chen, L. S. ; Wu, H. K. ; Chen, D. R. / The management of papillary lesion of the breast by core needle biopsy. In: European Journal of Surgical Oncology. 2009 ; Vol. 35, No. 1. pp. 21-24.
@article{ae7dfff0a10447329834c90a4753b8c9,
title = "The management of papillary lesion of the breast by core needle biopsy",
abstract = "Background: The purpose of this study was to determine the accuracy of core needle biopsy (CNB) diagnoses of papillary breast lesions, and to identify the risk factors and histologic features, compared with excisional biopsy (EB). Method: We retrospectively reviewed 1682 sonographically guided core needle biopsies performed at one single medical center from January 2001 through December 2005, and identified 41 papillary lesions. Surgical correlation was available for 35 cases, 2 cases were loss follow-up and 4 cases diagnosed as papilloma by core needle biopsy were followed up with imaging for at least 24 months. Results: The pathologic diagnoses for the 35 papillary lesions obtained at core biopsy were benign in 24 cases, atypical in 7, and malignant in 4. Of those diagnosed as benign lesions at CNB, 7/24 turned out to be malignant. In the hyperplasia group, 5/7 were malignant. The total upgrade rate was 39{\%}. The positive predict value was 100{\%} and negative predict value was 61{\%}. Conclusion: All papillary lesions of the breast diagnosed by CNB should be excised because a substantial number of lesions were upgraded of diagnoses at excision.",
keywords = "Core needle biopsy, Papillary lesion",
author = "Tseng, {H. S.} and Chen, {Y. L.} and Chen, {S. T.} and Wu, {Y. C.} and Kuo, {S. J.} and Chen, {L. S.} and Wu, {H. K.} and Chen, {D. R.}",
year = "2009",
month = "1",
doi = "10.1016/j.ejso.2008.06.004",
language = "English",
volume = "35",
pages = "21--24",
journal = "European Journal of Surgical Oncology",
issn = "0748-7983",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - The management of papillary lesion of the breast by core needle biopsy

AU - Tseng, H. S.

AU - Chen, Y. L.

AU - Chen, S. T.

AU - Wu, Y. C.

AU - Kuo, S. J.

AU - Chen, L. S.

AU - Wu, H. K.

AU - Chen, D. R.

PY - 2009/1

Y1 - 2009/1

N2 - Background: The purpose of this study was to determine the accuracy of core needle biopsy (CNB) diagnoses of papillary breast lesions, and to identify the risk factors and histologic features, compared with excisional biopsy (EB). Method: We retrospectively reviewed 1682 sonographically guided core needle biopsies performed at one single medical center from January 2001 through December 2005, and identified 41 papillary lesions. Surgical correlation was available for 35 cases, 2 cases were loss follow-up and 4 cases diagnosed as papilloma by core needle biopsy were followed up with imaging for at least 24 months. Results: The pathologic diagnoses for the 35 papillary lesions obtained at core biopsy were benign in 24 cases, atypical in 7, and malignant in 4. Of those diagnosed as benign lesions at CNB, 7/24 turned out to be malignant. In the hyperplasia group, 5/7 were malignant. The total upgrade rate was 39%. The positive predict value was 100% and negative predict value was 61%. Conclusion: All papillary lesions of the breast diagnosed by CNB should be excised because a substantial number of lesions were upgraded of diagnoses at excision.

AB - Background: The purpose of this study was to determine the accuracy of core needle biopsy (CNB) diagnoses of papillary breast lesions, and to identify the risk factors and histologic features, compared with excisional biopsy (EB). Method: We retrospectively reviewed 1682 sonographically guided core needle biopsies performed at one single medical center from January 2001 through December 2005, and identified 41 papillary lesions. Surgical correlation was available for 35 cases, 2 cases were loss follow-up and 4 cases diagnosed as papilloma by core needle biopsy were followed up with imaging for at least 24 months. Results: The pathologic diagnoses for the 35 papillary lesions obtained at core biopsy were benign in 24 cases, atypical in 7, and malignant in 4. Of those diagnosed as benign lesions at CNB, 7/24 turned out to be malignant. In the hyperplasia group, 5/7 were malignant. The total upgrade rate was 39%. The positive predict value was 100% and negative predict value was 61%. Conclusion: All papillary lesions of the breast diagnosed by CNB should be excised because a substantial number of lesions were upgraded of diagnoses at excision.

KW - Core needle biopsy

KW - Papillary lesion

UR - http://www.scopus.com/inward/record.url?scp=57549101920&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=57549101920&partnerID=8YFLogxK

U2 - 10.1016/j.ejso.2008.06.004

DO - 10.1016/j.ejso.2008.06.004

M3 - Article

VL - 35

SP - 21

EP - 24

JO - European Journal of Surgical Oncology

JF - European Journal of Surgical Oncology

SN - 0748-7983

IS - 1

ER -