The impact of smoking in primary spontaneous pneumothorax

Yeung Leung Cheng, Tsai Wang Huang, Chih Kung Lin, Shih Chun Lee, Ching Tzao, Jen Chih Chen, Hung Chang

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Background: The crucial role of cigarette smoking in the development of pneumothorax is unclear because nonsmokers can also develop primary spontaneous pneumothorax. The purpose of this study was to clarify the pathophysiologic effects of cigarette smoking and its clinical correlations in primary spontaneous pneumothorax. Methods: Included were 115 specimens of lung tissue from patients with primary spontaneous pneumothorax who underwent video-assisted thoracoscopic surgery from January 2001 to December 2002. We reviewed the clinical features of 56 smokers and 59 nonsmokers with an average follow-up of 67 months. The pathologic findings of resected lung specimens were analyzed retrospectively. Results: There were no statistical differences in sex, age, body height, body weight, body mass index, or the presence of blebs/bullae on computed tomography scans of the lung or under thoracoscopy between the 2 groups. In the smoking group, patients had more extensive respiratory bronchiolitis (P <.001), a high prevalence of tobacco pigmentation (P <.001), and a higher recurrence rate without or after surgery than the nonsmoking group (57% vs 22%, P = .001 and 8.9% vs 1.7%, P = .02, respectively). Patients with extensive respiratory bronchiolitis had significantly higher nonoperative and postoperative recurrences than patients with nonextensive respiratory bronchiolitis (P = .004 and P <.001, respectively). Conclusion: Cigarette smoking is associated with the pathophysiologic consequences of extensive respiratory bronchiolitis, which had a significant impact on the recurrence rates of primary spontaneous pneumothorax.

Original languageEnglish
Pages (from-to)192-195
Number of pages4
JournalJournal of Thoracic and Cardiovascular Surgery
Volume138
Issue number1
DOIs
Publication statusPublished - Jul 2009
Externally publishedYes

Fingerprint

Pneumothorax
Bronchiolitis
Smoking
Blister
Recurrence
Lung
Video-Assisted Thoracic Surgery
Thoracoscopy
Body Height
Pigmentation
Sex Characteristics
Tobacco
Body Mass Index
Tomography
Body Weight
Primary Spontaneous Pneumothorax

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery

Cite this

Cheng, Y. L., Huang, T. W., Lin, C. K., Lee, S. C., Tzao, C., Chen, J. C., & Chang, H. (2009). The impact of smoking in primary spontaneous pneumothorax. Journal of Thoracic and Cardiovascular Surgery, 138(1), 192-195. https://doi.org/10.1016/j.jtcvs.2008.12.019

The impact of smoking in primary spontaneous pneumothorax. / Cheng, Yeung Leung; Huang, Tsai Wang; Lin, Chih Kung; Lee, Shih Chun; Tzao, Ching; Chen, Jen Chih; Chang, Hung.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 138, No. 1, 07.2009, p. 192-195.

Research output: Contribution to journalArticle

Cheng, Yeung Leung ; Huang, Tsai Wang ; Lin, Chih Kung ; Lee, Shih Chun ; Tzao, Ching ; Chen, Jen Chih ; Chang, Hung. / The impact of smoking in primary spontaneous pneumothorax. In: Journal of Thoracic and Cardiovascular Surgery. 2009 ; Vol. 138, No. 1. pp. 192-195.
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