Abstract
Aims: The present study aims to examine neuropsychological impairments by comorbidity and gender among patients with alcohol dependence. Methods: The study sample is comprised of 123 subjects who fulfilled a Diagnostic and Statistical Manual of Mental Disorders 4th Edition (DSM-IV) diagnosis of alcohol dependence from January 2006 to December 2007. Subjects were asked to complete the following psychological tests: the Barratt Impulsivity Scale (BIS), Wechsler Adult Intelligence Scale, Wechsler Memory Scale and Color Trails Test. We compared the results of neuropsychological assessments based on two types of classifications: people with comorbid depression and people without comorbidity; females and males. Results: The immediate visual memory and the BIS scores in patients with comorbid depression were significantly different from the scores in patients without comorbidity. In addition, females performed significantly poorer on the Working Memory Index than males and had a later age of regular drinking. Conclusions: Further investigation of the mechanism associated with the gender difference on cognition and exploration of the temporal relationship between alcohol dependence and depressive disorder on the cognitive aspect is needed.
| Original language | English |
|---|---|
| Article number | agq016 |
| Pages (from-to) | 231-236 |
| Number of pages | 6 |
| Journal | Alcohol and Alcoholism |
| Volume | 45 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 29 2010 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine (miscellaneous)
- Psychiatry and Mental health
- Toxicology
Cite this
The effects of gender and a co-occurring depressive disorder on neurocognitive functioning in patients with alcohol dependence. / Liu, I. Chao; Chiu, Chen Huan; Yang, Tsung Tsair.
In: Alcohol and Alcoholism, Vol. 45, No. 3, agq016, 29.03.2010, p. 231-236.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The effects of gender and a co-occurring depressive disorder on neurocognitive functioning in patients with alcohol dependence
AU - Liu, I. Chao
AU - Chiu, Chen Huan
AU - Yang, Tsung Tsair
PY - 2010/3/29
Y1 - 2010/3/29
N2 - Aims: The present study aims to examine neuropsychological impairments by comorbidity and gender among patients with alcohol dependence. Methods: The study sample is comprised of 123 subjects who fulfilled a Diagnostic and Statistical Manual of Mental Disorders 4th Edition (DSM-IV) diagnosis of alcohol dependence from January 2006 to December 2007. Subjects were asked to complete the following psychological tests: the Barratt Impulsivity Scale (BIS), Wechsler Adult Intelligence Scale, Wechsler Memory Scale and Color Trails Test. We compared the results of neuropsychological assessments based on two types of classifications: people with comorbid depression and people without comorbidity; females and males. Results: The immediate visual memory and the BIS scores in patients with comorbid depression were significantly different from the scores in patients without comorbidity. In addition, females performed significantly poorer on the Working Memory Index than males and had a later age of regular drinking. Conclusions: Further investigation of the mechanism associated with the gender difference on cognition and exploration of the temporal relationship between alcohol dependence and depressive disorder on the cognitive aspect is needed.
AB - Aims: The present study aims to examine neuropsychological impairments by comorbidity and gender among patients with alcohol dependence. Methods: The study sample is comprised of 123 subjects who fulfilled a Diagnostic and Statistical Manual of Mental Disorders 4th Edition (DSM-IV) diagnosis of alcohol dependence from January 2006 to December 2007. Subjects were asked to complete the following psychological tests: the Barratt Impulsivity Scale (BIS), Wechsler Adult Intelligence Scale, Wechsler Memory Scale and Color Trails Test. We compared the results of neuropsychological assessments based on two types of classifications: people with comorbid depression and people without comorbidity; females and males. Results: The immediate visual memory and the BIS scores in patients with comorbid depression were significantly different from the scores in patients without comorbidity. In addition, females performed significantly poorer on the Working Memory Index than males and had a later age of regular drinking. Conclusions: Further investigation of the mechanism associated with the gender difference on cognition and exploration of the temporal relationship between alcohol dependence and depressive disorder on the cognitive aspect is needed.
UR - http://www.scopus.com/inward/record.url?scp=77951890073&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951890073&partnerID=8YFLogxK
U2 - 10.1093/alcalc/agq016
DO - 10.1093/alcalc/agq016
M3 - Article
C2 - 20353953
AN - SCOPUS:77951890073
VL - 45
SP - 231
EP - 236
JO - Alcohol and Alcoholism
JF - Alcohol and Alcoholism
SN - 0735-0414
IS - 3
M1 - agq016
ER -