Abstract

Objective. To determine the effects of 12-week exercise programme on ambulatory function, free-living daily physical activity and health-related quality of life in disabled older patients with intermittent claudication. Design. Prospective, randomized controlled trial. Setting. University Medical Center and Veterans Affairs Medical Center, Taipei, Taiwan. Subjects. Thirty-two of 64 patients with Fontaine stage II peripheral arterial occlusive disease (PAOD) were randomized to exercise training and 32 to usual care control. Five patients from the exercise group and six patients from the control group dropped out, leaving 27 and 26 patients, respectively, completing the study in each group. Interventions. Twelve weeks of treadmill exercise training. Main outcome measures. Treadmill walking time to onset of claudication pain and to maximal claudication pain, 6-min walk distance, self-reported ambulatory ability and perceived health-related quality of life (QOL). Results. Compliance of exercise programme was 83% of the possible sessions. Exercise training increased treadmill walking time to onset of claudication pain by 88% (P <0.001), time to maximal pain by 70% (P <0.001), and 6-min walk distance by 21% (P <0.001). Subjects. Perception of health-related QOL improved from 12% to 178% in the exercise group. These improvements were significantly better than the changes in the control group (P <0.05). Conclusions. Significant improvements in claudication following 12-week exercise training in elderly PAOD patients were observed. Increase in treadmill walking time to maximal claudication pain in these patients translated into the improvement of perceived physical health, which enabled the patients to become more functionally independent.

Original languageEnglish
Pages (from-to)448-455
Number of pages8
JournalJournal of Internal Medicine
Volume252
Issue number5
DOIs
Publication statusPublished - Nov 1 2002

Fingerprint

Arterial Occlusive Diseases
Peripheral Arterial Disease
Health Status
Walking
Exercise
Pain
Quality of Life
Intermittent Claudication
Control Groups
Aptitude
Veterans
Taiwan
Compliance
Randomized Controlled Trials
Outcome Assessment (Health Care)

Keywords

  • Exercise training
  • Intermittent claudication
  • Peripheral arterial occlusive disease
  • Quality of life
  • Treadmill

ASJC Scopus subject areas

  • Internal Medicine

Cite this

@article{cbd84679e7094abe8a852e5158bc15fa,
title = "The effects of exercise training on walking function and perception of health status in elderly patients with peripheral arterial occlusive disease",
abstract = "Objective. To determine the effects of 12-week exercise programme on ambulatory function, free-living daily physical activity and health-related quality of life in disabled older patients with intermittent claudication. Design. Prospective, randomized controlled trial. Setting. University Medical Center and Veterans Affairs Medical Center, Taipei, Taiwan. Subjects. Thirty-two of 64 patients with Fontaine stage II peripheral arterial occlusive disease (PAOD) were randomized to exercise training and 32 to usual care control. Five patients from the exercise group and six patients from the control group dropped out, leaving 27 and 26 patients, respectively, completing the study in each group. Interventions. Twelve weeks of treadmill exercise training. Main outcome measures. Treadmill walking time to onset of claudication pain and to maximal claudication pain, 6-min walk distance, self-reported ambulatory ability and perceived health-related quality of life (QOL). Results. Compliance of exercise programme was 83{\%} of the possible sessions. Exercise training increased treadmill walking time to onset of claudication pain by 88{\%} (P <0.001), time to maximal pain by 70{\%} (P <0.001), and 6-min walk distance by 21{\%} (P <0.001). Subjects. Perception of health-related QOL improved from 12{\%} to 178{\%} in the exercise group. These improvements were significantly better than the changes in the control group (P <0.05). Conclusions. Significant improvements in claudication following 12-week exercise training in elderly PAOD patients were observed. Increase in treadmill walking time to maximal claudication pain in these patients translated into the improvement of perceived physical health, which enabled the patients to become more functionally independent.",
keywords = "Exercise training, Intermittent claudication, Peripheral arterial occlusive disease, Quality of life, Treadmill",
author = "Tsai, {Jen Chen} and P. Chan and Chia-Hui Wang and C. Jeng and Hsieh, {M. H.} and Kao, {P. F.} and Chen, {Y. J.} and Liu, {J. C.}",
year = "2002",
month = "11",
day = "1",
doi = "10.1046/j.1365-2796.2002.01055.x",
language = "English",
volume = "252",
pages = "448--455",
journal = "Journal of Internal Medicine",
issn = "0954-6820",
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TY - JOUR

T1 - The effects of exercise training on walking function and perception of health status in elderly patients with peripheral arterial occlusive disease

AU - Tsai, Jen Chen

AU - Chan, P.

AU - Wang, Chia-Hui

AU - Jeng, C.

AU - Hsieh, M. H.

AU - Kao, P. F.

AU - Chen, Y. J.

AU - Liu, J. C.

PY - 2002/11/1

Y1 - 2002/11/1

N2 - Objective. To determine the effects of 12-week exercise programme on ambulatory function, free-living daily physical activity and health-related quality of life in disabled older patients with intermittent claudication. Design. Prospective, randomized controlled trial. Setting. University Medical Center and Veterans Affairs Medical Center, Taipei, Taiwan. Subjects. Thirty-two of 64 patients with Fontaine stage II peripheral arterial occlusive disease (PAOD) were randomized to exercise training and 32 to usual care control. Five patients from the exercise group and six patients from the control group dropped out, leaving 27 and 26 patients, respectively, completing the study in each group. Interventions. Twelve weeks of treadmill exercise training. Main outcome measures. Treadmill walking time to onset of claudication pain and to maximal claudication pain, 6-min walk distance, self-reported ambulatory ability and perceived health-related quality of life (QOL). Results. Compliance of exercise programme was 83% of the possible sessions. Exercise training increased treadmill walking time to onset of claudication pain by 88% (P <0.001), time to maximal pain by 70% (P <0.001), and 6-min walk distance by 21% (P <0.001). Subjects. Perception of health-related QOL improved from 12% to 178% in the exercise group. These improvements were significantly better than the changes in the control group (P <0.05). Conclusions. Significant improvements in claudication following 12-week exercise training in elderly PAOD patients were observed. Increase in treadmill walking time to maximal claudication pain in these patients translated into the improvement of perceived physical health, which enabled the patients to become more functionally independent.

AB - Objective. To determine the effects of 12-week exercise programme on ambulatory function, free-living daily physical activity and health-related quality of life in disabled older patients with intermittent claudication. Design. Prospective, randomized controlled trial. Setting. University Medical Center and Veterans Affairs Medical Center, Taipei, Taiwan. Subjects. Thirty-two of 64 patients with Fontaine stage II peripheral arterial occlusive disease (PAOD) were randomized to exercise training and 32 to usual care control. Five patients from the exercise group and six patients from the control group dropped out, leaving 27 and 26 patients, respectively, completing the study in each group. Interventions. Twelve weeks of treadmill exercise training. Main outcome measures. Treadmill walking time to onset of claudication pain and to maximal claudication pain, 6-min walk distance, self-reported ambulatory ability and perceived health-related quality of life (QOL). Results. Compliance of exercise programme was 83% of the possible sessions. Exercise training increased treadmill walking time to onset of claudication pain by 88% (P <0.001), time to maximal pain by 70% (P <0.001), and 6-min walk distance by 21% (P <0.001). Subjects. Perception of health-related QOL improved from 12% to 178% in the exercise group. These improvements were significantly better than the changes in the control group (P <0.05). Conclusions. Significant improvements in claudication following 12-week exercise training in elderly PAOD patients were observed. Increase in treadmill walking time to maximal claudication pain in these patients translated into the improvement of perceived physical health, which enabled the patients to become more functionally independent.

KW - Exercise training

KW - Intermittent claudication

KW - Peripheral arterial occlusive disease

KW - Quality of life

KW - Treadmill

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