綠藻對於餵食高油脂高膽固醇飼料之大白鼠脂質代謝的影響

Translated title of the contribution: The effects of chlorella on lipid metabolism in rats fed with high fat and high cholesterol diet

S. C. Yang, T. I. Huang, C. C. Huang, Ming-Che Hsieh, W. C. Chiu, C. J. Cheng, J. R. Chen

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The purpose of this study was to investigate the effects of chlorella on the lipid metabolism of rats fed with a high fat and high cholesterol diet. Forty Wistar rats were divided into five groups (control, AD0, AD1, AD5 and AD10). In the control group, rats were fed normal diets (5% soybean oil). In the AD0, AD1, AD5 and AD10 groups, rats were fed with high fat and high cholesterol diets (15% soybean oil and 1% cholesterol) containing 0%, 1%, 5% and 10% chlorella, respectively. The experimental period was 8 weeks. The results showed that the total plasma cholesterol (TC) and low density lipoprotein-cholesterol (LDL-C) levels were significantly tower in the AD1 group at weeks 4, 6 and 8; and in the AD10 group at weeks 6 than in the ADO group. Furthermore, triglyceride (TG) levels were significantly lower in the AD1, AD5 and AD10 than in AD0 group throughout the experimental period. The high density lipoprotein-cholesterol (HDL-C) levels were significantly higher in the AD1, AD5 and AD10 groups than in the AD0 group. When compared to the ADO group, the liver TC content in the AD1, AD5 and AD10 groups were significantly decreased by 30%, 68%, 77%, and the TG levels were decreased by 50%, 67%, 68%, respectively. However, the fecal cholesterol and bile acid levels were significantly decreased in the AD1 and AD10 groups than in the AD0 and AD5 groups.

Original languageTraditional Chinese
Pages (from-to)22-31
Number of pages10
JournalNutritional Sciences Journal
Volume26
Issue number1
Publication statusPublished - 2001

Fingerprint

Chlorella
High Fat Diet
high fat diet
Lipid Metabolism
lipid metabolism
Cholesterol
cholesterol
rats
lipids
soybean oil
triacylglycerols
Soybean Oil
bile acids
low density lipoprotein cholesterol
high density lipoprotein cholesterol
Triglycerides
Control Groups
liver
Alzheimer Disease 10
Bile Acids and Salts

Keywords

  • Chlorella
  • Hyperlipidemia
  • Plasma lipid profile

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

Cite this

綠藻對於餵食高油脂高膽固醇飼料之大白鼠脂質代謝的影響. / Yang, S. C.; Huang, T. I.; Huang, C. C.; Hsieh, Ming-Che; Chiu, W. C.; Cheng, C. J.; Chen, J. R.

In: Nutritional Sciences Journal, Vol. 26, No. 1, 2001, p. 22-31.

Research output: Contribution to journalArticle

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title = "綠藻對於餵食高油脂高膽固醇飼料之大白鼠脂質代謝的影響",
abstract = "本實驗之目的在探討高油脂、高膽固醇飲食條件下綠藻對大白鼠體內脂質代謝的影響。將40隻Wistar系大白鼠分為對照組、AD0、AD1、AD5以及AD10等5組。以正常飼料(大豆油5{\%})飼養對照組,而以高油脂(大豆油15{\%})、高膽固醇(膽固醇1{\%})同時添加0{\%}、1{\%}、5{\%}或10{\%}綠藻粉之飼料飼養AD0、AD1、AD5以及AD10組。實驗期為八週。結果顯示:在TC和LDL-C濃度方面與AD0組比較之下,AD1組在第4、6、8週時顯著較低,而AD10組在第6週時顯著較低。在TG濃度方面與AD0組比較之下AD1、AD5和AD10組在第2、4、6、8週時皆明顯較低。在HDL-C濃度方面與AD0組比較之下AD1、AD5和AD10組在第2、4、6、8週時皆明顯較高。另外,肝中的TC與AD0組比較之下,AD1、AD5、AD10組各降低30{\%}、68{\%}、77{\%},而肝中的TG與AD0組比較之下,各綠藻添加組則各降低50{\%}、67{\%}、68{\%}。與AD0組比較時,AD1以及AD10組之糞便膽固醇量和膽酸量則明顯降低。",
keywords = "Chlorella, Hyperlipidemia, Plasma lipid profile, 綠藻, 高脂血症, 血脂質",
author = "Yang, {S. C.} and Huang, {T. I.} and Huang, {C. C.} and Ming-Che Hsieh and Chiu, {W. C.} and Cheng, {C. J.} and Chen, {J. R.}",
year = "2001",
language = "繁體中文",
volume = "26",
pages = "22--31",
journal = "Journal of the Chinese Nutrition Society",
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AU - Yang, S. C.

AU - Huang, T. I.

AU - Huang, C. C.

AU - Hsieh, Ming-Che

AU - Chiu, W. C.

AU - Cheng, C. J.

AU - Chen, J. R.

PY - 2001

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AB - 本實驗之目的在探討高油脂、高膽固醇飲食條件下綠藻對大白鼠體內脂質代謝的影響。將40隻Wistar系大白鼠分為對照組、AD0、AD1、AD5以及AD10等5組。以正常飼料(大豆油5%)飼養對照組,而以高油脂(大豆油15%)、高膽固醇(膽固醇1%)同時添加0%、1%、5%或10%綠藻粉之飼料飼養AD0、AD1、AD5以及AD10組。實驗期為八週。結果顯示:在TC和LDL-C濃度方面與AD0組比較之下,AD1組在第4、6、8週時顯著較低,而AD10組在第6週時顯著較低。在TG濃度方面與AD0組比較之下AD1、AD5和AD10組在第2、4、6、8週時皆明顯較低。在HDL-C濃度方面與AD0組比較之下AD1、AD5和AD10組在第2、4、6、8週時皆明顯較高。另外,肝中的TC與AD0組比較之下,AD1、AD5、AD10組各降低30%、68%、77%,而肝中的TG與AD0組比較之下,各綠藻添加組則各降低50%、67%、68%。與AD0組比較時,AD1以及AD10組之糞便膽固醇量和膽酸量則明顯降低。

KW - Chlorella

KW - Hyperlipidemia

KW - Plasma lipid profile

KW - 綠藻

KW - 高脂血症

KW - 血脂質

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EP - 31

JO - Journal of the Chinese Nutrition Society

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