The clinical usefulness of ESR, CRP, and disease duration in ankylosing spondylitis: the product of these acute-phase reactants and disease duration is associated with patient’s poor physical mobility

Chun Hsiung Chen, Hung An Chen, Hsien Tzung Liao, Chin Hsiu Liu, Chang Youh Tsai, Chung Tei Chou

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We evaluated the clinical usefulness of ESR, CRP, and disease duration in ankylosing spondylitis (AS) disease severity. There were 156 Chinese AS patients included in Taiwan. Patients completed the questionnaires, containing demographic data, disease activity (BASDAI), functional status (BASFI), and patient’s global assessment (BASG). Meanwhile, patient’s physical mobility (BASMI) and acute-phase reactants, including ESR and CRP levels were measured. Receiver operating characteristic (ROC) plot analysis was used to evaluate the performance of ESR, CRP, and disease duration in the AS patients. ESR mildly correlated with BASFI (r = 0.176, p = 0.028) and disease duration (r = 0.214, p = 0.008), and moderately correlated with BASMI (r = 0.427, p 

Original languageEnglish
Pages (from-to)1263-1267
Number of pages5
JournalRheumatology International
Volume35
Issue number7
DOIs
Publication statusPublished - Feb 24 2015

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Acute-Phase Proteins
Ankylosing Spondylitis
Taiwan
ROC Curve
Demography

Keywords

  • Ankylosing spondylitis
  • CRP
  • Disease duration
  • ESR
  • Physical mobility

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

Cite this

The clinical usefulness of ESR, CRP, and disease duration in ankylosing spondylitis : the product of these acute-phase reactants and disease duration is associated with patient’s poor physical mobility. / Chen, Chun Hsiung; Chen, Hung An; Liao, Hsien Tzung; Liu, Chin Hsiu; Tsai, Chang Youh; Chou, Chung Tei.

In: Rheumatology International, Vol. 35, No. 7, 24.02.2015, p. 1263-1267.

Research output: Contribution to journalArticle

Chen, Chun Hsiung ; Chen, Hung An ; Liao, Hsien Tzung ; Liu, Chin Hsiu ; Tsai, Chang Youh ; Chou, Chung Tei. / The clinical usefulness of ESR, CRP, and disease duration in ankylosing spondylitis : the product of these acute-phase reactants and disease duration is associated with patient’s poor physical mobility. In: Rheumatology International. 2015 ; Vol. 35, No. 7. pp. 1263-1267.
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