The clinical features and prognosis of male lupus in Taiwan

D. M. Chang, C. C. Chang, S. Y. Kuo, S. J. Chu, M. L. Chang

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Our objective was to describe the clinical manifestations, laboratory data, and prognosis in male Chinese lupus patients in Taiwan. Seventy-two male lupus patients, diagnosed and followed in Tri-Service General Hospital between 1983 and 1996, were studied and their clinical data analyzed, retrospectively. The mean age at diagnosis was 34 ± 16 y (mean ± s.d., range: 13-82 y). The peak incidence of age at diagnosis was between 13 and 40 years. The three most frequent clinical manifestations were renal disease, 75%; malar rash, 61%; and arthritis, 53%. The three most frequent abnormal laboratory findings were anti-nuclear antibodies (ANA, 97%; hypocomplementemia, 76%: and anti-ds DNA, 57%. The 1-, 5-, and 10-year survival rates were 85%, 76%, and 75%, respectively. In summary, a higher frequency of renal disease, malar rash and photosensitivity, but a lower frequency of arthritis and lymphadenopathy were demonstrated in our 72 ethnic Chinese male Taiwanese lupus patients compared to previous reports of Caucasians. The prognosis seems to be similar to that of both Chinese and Caucasian males but seems to be poor when compared to either Chinese or Caucasian female lupus patients.

Original languageEnglish
Pages (from-to)462-468
Number of pages7
JournalLupus
Volume7
Issue number7
DOIs
Publication statusPublished - 1998
Externally publishedYes

Fingerprint

Taiwan
Exanthema
Arthritis
Kidney
General Hospitals
Anti-Idiotypic Antibodies
Survival Rate
DNA
Incidence

Keywords

  • Male
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

Chang, D. M., Chang, C. C., Kuo, S. Y., Chu, S. J., & Chang, M. L. (1998). The clinical features and prognosis of male lupus in Taiwan. Lupus, 7(7), 462-468. https://doi.org/10.1191/096120398678920479

The clinical features and prognosis of male lupus in Taiwan. / Chang, D. M.; Chang, C. C.; Kuo, S. Y.; Chu, S. J.; Chang, M. L.

In: Lupus, Vol. 7, No. 7, 1998, p. 462-468.

Research output: Contribution to journalArticle

Chang, DM, Chang, CC, Kuo, SY, Chu, SJ & Chang, ML 1998, 'The clinical features and prognosis of male lupus in Taiwan', Lupus, vol. 7, no. 7, pp. 462-468. https://doi.org/10.1191/096120398678920479
Chang, D. M. ; Chang, C. C. ; Kuo, S. Y. ; Chu, S. J. ; Chang, M. L. / The clinical features and prognosis of male lupus in Taiwan. In: Lupus. 1998 ; Vol. 7, No. 7. pp. 462-468.
@article{6582a8b5bbd44de6a741396a904ab088,
title = "The clinical features and prognosis of male lupus in Taiwan",
abstract = "Our objective was to describe the clinical manifestations, laboratory data, and prognosis in male Chinese lupus patients in Taiwan. Seventy-two male lupus patients, diagnosed and followed in Tri-Service General Hospital between 1983 and 1996, were studied and their clinical data analyzed, retrospectively. The mean age at diagnosis was 34 ± 16 y (mean ± s.d., range: 13-82 y). The peak incidence of age at diagnosis was between 13 and 40 years. The three most frequent clinical manifestations were renal disease, 75{\%}; malar rash, 61{\%}; and arthritis, 53{\%}. The three most frequent abnormal laboratory findings were anti-nuclear antibodies (ANA, 97{\%}; hypocomplementemia, 76{\%}: and anti-ds DNA, 57{\%}. The 1-, 5-, and 10-year survival rates were 85{\%}, 76{\%}, and 75{\%}, respectively. In summary, a higher frequency of renal disease, malar rash and photosensitivity, but a lower frequency of arthritis and lymphadenopathy were demonstrated in our 72 ethnic Chinese male Taiwanese lupus patients compared to previous reports of Caucasians. The prognosis seems to be similar to that of both Chinese and Caucasian males but seems to be poor when compared to either Chinese or Caucasian female lupus patients.",
keywords = "Male, Systemic lupus erythematosus",
author = "Chang, {D. M.} and Chang, {C. C.} and Kuo, {S. Y.} and Chu, {S. J.} and Chang, {M. L.}",
year = "1998",
doi = "10.1191/096120398678920479",
language = "English",
volume = "7",
pages = "462--468",
journal = "Lupus",
issn = "0961-2033",
publisher = "SAGE Publications Ltd",
number = "7",

}

TY - JOUR

T1 - The clinical features and prognosis of male lupus in Taiwan

AU - Chang, D. M.

AU - Chang, C. C.

AU - Kuo, S. Y.

AU - Chu, S. J.

AU - Chang, M. L.

PY - 1998

Y1 - 1998

N2 - Our objective was to describe the clinical manifestations, laboratory data, and prognosis in male Chinese lupus patients in Taiwan. Seventy-two male lupus patients, diagnosed and followed in Tri-Service General Hospital between 1983 and 1996, were studied and their clinical data analyzed, retrospectively. The mean age at diagnosis was 34 ± 16 y (mean ± s.d., range: 13-82 y). The peak incidence of age at diagnosis was between 13 and 40 years. The three most frequent clinical manifestations were renal disease, 75%; malar rash, 61%; and arthritis, 53%. The three most frequent abnormal laboratory findings were anti-nuclear antibodies (ANA, 97%; hypocomplementemia, 76%: and anti-ds DNA, 57%. The 1-, 5-, and 10-year survival rates were 85%, 76%, and 75%, respectively. In summary, a higher frequency of renal disease, malar rash and photosensitivity, but a lower frequency of arthritis and lymphadenopathy were demonstrated in our 72 ethnic Chinese male Taiwanese lupus patients compared to previous reports of Caucasians. The prognosis seems to be similar to that of both Chinese and Caucasian males but seems to be poor when compared to either Chinese or Caucasian female lupus patients.

AB - Our objective was to describe the clinical manifestations, laboratory data, and prognosis in male Chinese lupus patients in Taiwan. Seventy-two male lupus patients, diagnosed and followed in Tri-Service General Hospital between 1983 and 1996, were studied and their clinical data analyzed, retrospectively. The mean age at diagnosis was 34 ± 16 y (mean ± s.d., range: 13-82 y). The peak incidence of age at diagnosis was between 13 and 40 years. The three most frequent clinical manifestations were renal disease, 75%; malar rash, 61%; and arthritis, 53%. The three most frequent abnormal laboratory findings were anti-nuclear antibodies (ANA, 97%; hypocomplementemia, 76%: and anti-ds DNA, 57%. The 1-, 5-, and 10-year survival rates were 85%, 76%, and 75%, respectively. In summary, a higher frequency of renal disease, malar rash and photosensitivity, but a lower frequency of arthritis and lymphadenopathy were demonstrated in our 72 ethnic Chinese male Taiwanese lupus patients compared to previous reports of Caucasians. The prognosis seems to be similar to that of both Chinese and Caucasian males but seems to be poor when compared to either Chinese or Caucasian female lupus patients.

KW - Male

KW - Systemic lupus erythematosus

UR - http://www.scopus.com/inward/record.url?scp=0031695591&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031695591&partnerID=8YFLogxK

U2 - 10.1191/096120398678920479

DO - 10.1191/096120398678920479

M3 - Article

C2 - 9796848

AN - SCOPUS:0031695591

VL - 7

SP - 462

EP - 468

JO - Lupus

JF - Lupus

SN - 0961-2033

IS - 7

ER -