The best usage of aspirin in primary prevention - Indication, dosage and ethnic issues

Chung Sheng Lin, Wayne H H Sheu, Chang Ming Chern, Chau Chung Wu, Low Tone Ho, Chung Y. Hsu, Tsui Lieh Hsu, Yuk Keung Lo, Ming Fong Chen

Research output: Contribution to journalArticle

Abstract

Aspirin is a well-known drug applied in clinical therapy. However, results of aspirin researches and clinical trials are different from traditional therapeutical guidelines. Some new conclusions emerged. Aspirin takes in a prevention role in some diseases, such as cardiovascular (CV) events, diabetes, and metabolic syndrome. However, how to apply aspirin in primary prevention still needs more discussion. In this article, we discuss the effect of aspirin in the field of cardiology, stroke, diabetes and pharmacology. We also discuss the dosage and appropriate usage of aspirin in Taiwan's population. The content of this article included the view points of the benefit of aspirin in the prevention of CV events from cardiologist's, diabetologist's and neurologist's view. We also discuss the starring role of aspirin from pharmacological issues or clinical reality? The conclusions are that enteric-coated aspirin has good gastrointestinal tolerability than common caplets; Anti-platelet therapies such as long-term use of low dose aspirin (75-150 mg/day) can significantly reduce cardiovascular events; Aspirin can reduce the risk of first stroke in women and myocardial infarction in man; It also can reduce the risk of cardiovascular events in diabetes. Besides, American Heart Association and American Diabetes Association recommend that aspirin can be used as primary and secondary prevention in high risk population of cardiovascular disease. The individual management is recommended when people who have high risk of CV events and use aspirin in primary or secondary prevention.

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalJournal of Internal Medicine of Taiwan
Volume18
Issue number1
Publication statusPublished - Feb 2007

Fingerprint

Primary Prevention
Aspirin
Secondary Prevention
Stroke
Pharmacology
Cardiology
Taiwan
Population
Cardiovascular Diseases
Blood Platelets
Myocardial Infarction
Clinical Trials
Guidelines

Keywords

  • Aspirin
  • Diabetes
  • Dosage
  • Metabolic syndrome
  • Primary prevention
  • Stroke

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Lin, C. S., Sheu, W. H. H., Chern, C. M., Wu, C. C., Ho, L. T., Hsu, C. Y., ... Chen, M. F. (2007). The best usage of aspirin in primary prevention - Indication, dosage and ethnic issues. Journal of Internal Medicine of Taiwan, 18(1), 1-10.

The best usage of aspirin in primary prevention - Indication, dosage and ethnic issues. / Lin, Chung Sheng; Sheu, Wayne H H; Chern, Chang Ming; Wu, Chau Chung; Ho, Low Tone; Hsu, Chung Y.; Hsu, Tsui Lieh; Lo, Yuk Keung; Chen, Ming Fong.

In: Journal of Internal Medicine of Taiwan, Vol. 18, No. 1, 02.2007, p. 1-10.

Research output: Contribution to journalArticle

Lin, CS, Sheu, WHH, Chern, CM, Wu, CC, Ho, LT, Hsu, CY, Hsu, TL, Lo, YK & Chen, MF 2007, 'The best usage of aspirin in primary prevention - Indication, dosage and ethnic issues', Journal of Internal Medicine of Taiwan, vol. 18, no. 1, pp. 1-10.
Lin, Chung Sheng ; Sheu, Wayne H H ; Chern, Chang Ming ; Wu, Chau Chung ; Ho, Low Tone ; Hsu, Chung Y. ; Hsu, Tsui Lieh ; Lo, Yuk Keung ; Chen, Ming Fong. / The best usage of aspirin in primary prevention - Indication, dosage and ethnic issues. In: Journal of Internal Medicine of Taiwan. 2007 ; Vol. 18, No. 1. pp. 1-10.
@article{fad2297cd5244186ad5d210e319b8389,
title = "The best usage of aspirin in primary prevention - Indication, dosage and ethnic issues",
abstract = "Aspirin is a well-known drug applied in clinical therapy. However, results of aspirin researches and clinical trials are different from traditional therapeutical guidelines. Some new conclusions emerged. Aspirin takes in a prevention role in some diseases, such as cardiovascular (CV) events, diabetes, and metabolic syndrome. However, how to apply aspirin in primary prevention still needs more discussion. In this article, we discuss the effect of aspirin in the field of cardiology, stroke, diabetes and pharmacology. We also discuss the dosage and appropriate usage of aspirin in Taiwan's population. The content of this article included the view points of the benefit of aspirin in the prevention of CV events from cardiologist's, diabetologist's and neurologist's view. We also discuss the starring role of aspirin from pharmacological issues or clinical reality? The conclusions are that enteric-coated aspirin has good gastrointestinal tolerability than common caplets; Anti-platelet therapies such as long-term use of low dose aspirin (75-150 mg/day) can significantly reduce cardiovascular events; Aspirin can reduce the risk of first stroke in women and myocardial infarction in man; It also can reduce the risk of cardiovascular events in diabetes. Besides, American Heart Association and American Diabetes Association recommend that aspirin can be used as primary and secondary prevention in high risk population of cardiovascular disease. The individual management is recommended when people who have high risk of CV events and use aspirin in primary or secondary prevention.",
keywords = "Aspirin, Diabetes, Dosage, Metabolic syndrome, Primary prevention, Stroke",
author = "Lin, {Chung Sheng} and Sheu, {Wayne H H} and Chern, {Chang Ming} and Wu, {Chau Chung} and Ho, {Low Tone} and Hsu, {Chung Y.} and Hsu, {Tsui Lieh} and Lo, {Yuk Keung} and Chen, {Ming Fong}",
year = "2007",
month = "2",
language = "English",
volume = "18",
pages = "1--10",
journal = "Journal of Internal Medicine of Taiwan",
issn = "1016-7390",
publisher = "臺灣內科醫學會",
number = "1",

}

TY - JOUR

T1 - The best usage of aspirin in primary prevention - Indication, dosage and ethnic issues

AU - Lin, Chung Sheng

AU - Sheu, Wayne H H

AU - Chern, Chang Ming

AU - Wu, Chau Chung

AU - Ho, Low Tone

AU - Hsu, Chung Y.

AU - Hsu, Tsui Lieh

AU - Lo, Yuk Keung

AU - Chen, Ming Fong

PY - 2007/2

Y1 - 2007/2

N2 - Aspirin is a well-known drug applied in clinical therapy. However, results of aspirin researches and clinical trials are different from traditional therapeutical guidelines. Some new conclusions emerged. Aspirin takes in a prevention role in some diseases, such as cardiovascular (CV) events, diabetes, and metabolic syndrome. However, how to apply aspirin in primary prevention still needs more discussion. In this article, we discuss the effect of aspirin in the field of cardiology, stroke, diabetes and pharmacology. We also discuss the dosage and appropriate usage of aspirin in Taiwan's population. The content of this article included the view points of the benefit of aspirin in the prevention of CV events from cardiologist's, diabetologist's and neurologist's view. We also discuss the starring role of aspirin from pharmacological issues or clinical reality? The conclusions are that enteric-coated aspirin has good gastrointestinal tolerability than common caplets; Anti-platelet therapies such as long-term use of low dose aspirin (75-150 mg/day) can significantly reduce cardiovascular events; Aspirin can reduce the risk of first stroke in women and myocardial infarction in man; It also can reduce the risk of cardiovascular events in diabetes. Besides, American Heart Association and American Diabetes Association recommend that aspirin can be used as primary and secondary prevention in high risk population of cardiovascular disease. The individual management is recommended when people who have high risk of CV events and use aspirin in primary or secondary prevention.

AB - Aspirin is a well-known drug applied in clinical therapy. However, results of aspirin researches and clinical trials are different from traditional therapeutical guidelines. Some new conclusions emerged. Aspirin takes in a prevention role in some diseases, such as cardiovascular (CV) events, diabetes, and metabolic syndrome. However, how to apply aspirin in primary prevention still needs more discussion. In this article, we discuss the effect of aspirin in the field of cardiology, stroke, diabetes and pharmacology. We also discuss the dosage and appropriate usage of aspirin in Taiwan's population. The content of this article included the view points of the benefit of aspirin in the prevention of CV events from cardiologist's, diabetologist's and neurologist's view. We also discuss the starring role of aspirin from pharmacological issues or clinical reality? The conclusions are that enteric-coated aspirin has good gastrointestinal tolerability than common caplets; Anti-platelet therapies such as long-term use of low dose aspirin (75-150 mg/day) can significantly reduce cardiovascular events; Aspirin can reduce the risk of first stroke in women and myocardial infarction in man; It also can reduce the risk of cardiovascular events in diabetes. Besides, American Heart Association and American Diabetes Association recommend that aspirin can be used as primary and secondary prevention in high risk population of cardiovascular disease. The individual management is recommended when people who have high risk of CV events and use aspirin in primary or secondary prevention.

KW - Aspirin

KW - Diabetes

KW - Dosage

KW - Metabolic syndrome

KW - Primary prevention

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=33947631360&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33947631360&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33947631360

VL - 18

SP - 1

EP - 10

JO - Journal of Internal Medicine of Taiwan

JF - Journal of Internal Medicine of Taiwan

SN - 1016-7390

IS - 1

ER -