The association between gender and outcome of patients with upper tract urothelial cancer

Yii-Her Chou, Wei-Chiao Chang, Wen-Jeng Wu, Ching-Chia Li, Hsin-Chih Yeh, Ming-Feng Hou, Ping-Song Chou, Mei-Hui Lee, Wei Pin Chang, Wei-Ming Li

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The incidence of upper tract urothelial cancer (UTUC) has gradually increased over the past 30 years. Although most reports have shown that UTUC occurs more frequently in men than in women, women have been found to have a worse prognosis than men. In Taiwan, a high incidence of UTUC has been reported, with an unusual minor predominance of female cases. The purpose of this study was to determine the influence of gender on the outcome of patients with UTUC after nephroureterectomy and bladder cuff excision. From January 1990 to December 2007, 301 patients diagnosed with UTUC were admitted at our institution. A retrospective analysis of the effect of gender on the clinical outcome was performed. We compared the 5-year bladder recurrence-free, progression-free, and disease-specific survival rates. While we did not observe any differences between men and women in bladder recurrence-free, progression-free, or disease-specific survival rates, we found that female patients had a significantly higher percentage of contralateral recurrence than the males (5.9% vs. 0.8%, p = 0.019).

Original languageEnglish
Pages (from-to)37-42
Number of pages6
JournalKaohsiung Journal of Medical Sciences
Volume29
Issue number1
DOIs
Publication statusPublished - Jan 2013

Fingerprint

Urinary Bladder
Neoplasms
Recurrence
Survival Rate
Incidence
Taiwan
Disease Progression

Keywords

  • Gender
  • Nephroureterectomy
  • Outcome
  • Upper tract urothelial cancer
  • Urothelial cancer

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The association between gender and outcome of patients with upper tract urothelial cancer. / Chou, Yii-Her; Chang, Wei-Chiao; Wu, Wen-Jeng; Li, Ching-Chia; Yeh, Hsin-Chih; Hou, Ming-Feng; Chou, Ping-Song; Lee, Mei-Hui; Chang, Wei Pin; Li, Wei-Ming.

In: Kaohsiung Journal of Medical Sciences, Vol. 29, No. 1, 01.2013, p. 37-42.

Research output: Contribution to journalArticle

Chou, Yii-Her ; Chang, Wei-Chiao ; Wu, Wen-Jeng ; Li, Ching-Chia ; Yeh, Hsin-Chih ; Hou, Ming-Feng ; Chou, Ping-Song ; Lee, Mei-Hui ; Chang, Wei Pin ; Li, Wei-Ming. / The association between gender and outcome of patients with upper tract urothelial cancer. In: Kaohsiung Journal of Medical Sciences. 2013 ; Vol. 29, No. 1. pp. 37-42.
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