The anticancer properties and apoptosis-inducing mechanisms of cinnamaldehyde and the herbal prescription Huang-Lian-Jie-Du-Tang (Huáng Lián Jiě Dú Tang) in human hepatoma cells

Liang Tzung Lin, Shu Jing Wu, Chun Ching Lin

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Huáng Lián Jiě Dú Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.

Original languageEnglish
Pages (from-to)227-233
Number of pages7
JournalJournal of Traditional and Complementary Medicine
Volume3
Issue number4
DOIs
Publication statusPublished - 2013

Fingerprint

Prescriptions
Hepatocellular Carcinoma
Apoptosis
Cinnamomum zeylanicum
Herbal Medicine
Traditional Medicine
Korea
Biological Products
Taiwan
China
Japan
Mortality
cinnamic aldehyde
oren gedoku to
Therapeutics
Neoplasms

Keywords

  • Anticancer
  • Apoptosis
  • Cinnamaldehyde
  • Hepatoma
  • Huang-Lian-Jie-Du-Tang

ASJC Scopus subject areas

  • Complementary and alternative medicine

Cite this

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title = "The anticancer properties and apoptosis-inducing mechanisms of cinnamaldehyde and the herbal prescription Huang-Lian-Jie-Du-Tang (Hu{\'a}ng Li{\'a}n Jiě D{\'u} Tang) in human hepatoma cells",
abstract = "Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Hu{\'a}ng Li{\'a}n Jiě D{\'u} Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.",
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TY - JOUR

T1 - The anticancer properties and apoptosis-inducing mechanisms of cinnamaldehyde and the herbal prescription Huang-Lian-Jie-Du-Tang (Huáng Lián Jiě Dú Tang) in human hepatoma cells

AU - Lin, Liang Tzung

AU - Wu, Shu Jing

AU - Lin, Chun Ching

PY - 2013

Y1 - 2013

N2 - Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Huáng Lián Jiě Dú Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.

AB - Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Huáng Lián Jiě Dú Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.

KW - Anticancer

KW - Apoptosis

KW - Cinnamaldehyde

KW - Hepatoma

KW - Huang-Lian-Jie-Du-Tang

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