The anticancer properties and apoptosis-inducing mechanisms of cinnamaldehyde and the herbal prescription Huang-Lian-Jie-Du-Tang (Huáng Lián Jiě Dú Tang) in human hepatoma cells

Liang Tzung Lin; Shu Jing Wu; Chun Ching Lin

doi:10.4103/2225-4110.119732

The anticancer properties and apoptosis-inducing mechanisms of cinnamaldehyde and the herbal prescription Huang-Lian-Jie-Du-Tang (Huáng Lián Jiě Dú Tang) in human hepatoma cells

Liang Tzung Lin, Shu Jing Wu, Chun Ching Lin

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Huáng Lián Jiě Dú Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.

Original language	English
Pages (from-to)	227-233
Number of pages	7
Journal	Journal of Traditional and Complementary Medicine
Volume	3
Issue number	4
DOIs	https://doi.org/10.4103/2225-4110.119732
Publication status	Published - 2013

Keywords

Anticancer
Apoptosis
Cinnamaldehyde
Hepatoma
Huang-Lian-Jie-Du-Tang

ASJC Scopus subject areas

Complementary and alternative medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4103/2225-4110.119732

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The anticancer properties and apoptosis-inducing mechanisms of cinnamaldehyde and the herbal prescription Huang-Lian-Jie-Du-Tang (Huáng Lián Jiě Dú Tang) in human hepatoma cells. / Lin, Liang Tzung; Wu, Shu Jing; Lin, Chun Ching.

In: Journal of Traditional and Complementary Medicine, Vol. 3, No. 4, 2013, p. 227-233.

Research output: Contribution to journal › Article › peer-review

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abstract = "Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Hu{\'a}ng Li{\'a}n Ji{\v e} D{\'u} Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.",

keywords = "Anticancer, Apoptosis, Cinnamaldehyde, Hepatoma, Huang-Lian-Jie-Du-Tang",

author = "Lin, {Liang Tzung} and Wu, {Shu Jing} and Lin, {Chun Ching}",

note = "Funding Information: LTL was supported by funding from Taipei Medical University (TMU101-AE3-Y19). CCL was supported by a research grant from the Committee on Chinese Medicine and Pharmacy, Department of Health, Executive Yuan of Taiwan (CCMP 95-RD-212). SJW received support from the National Science Council of Taiwan (NSC96-2313-B-041-004).",

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doi = "10.4103/2225-4110.119732",

language = "English",

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AU - Wu, Shu Jing

AU - Lin, Chun Ching

N1 - Funding Information: LTL was supported by funding from Taipei Medical University (TMU101-AE3-Y19). CCL was supported by a research grant from the Committee on Chinese Medicine and Pharmacy, Department of Health, Executive Yuan of Taiwan (CCMP 95-RD-212). SJW received support from the National Science Council of Taiwan (NSC96-2313-B-041-004).

PY - 2013

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N2 - Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Huáng Lián Jiě Dú Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.

AB - Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Huáng Lián Jiě Dú Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.

KW - Anticancer

KW - Apoptosis

KW - Cinnamaldehyde

KW - Hepatoma

KW - Huang-Lian-Jie-Du-Tang

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The anticancer properties and apoptosis-inducing mechanisms of cinnamaldehyde and the herbal prescription Huang-Lian-Jie-Du-Tang (Huáng Lián Jiě Dú Tang) in human hepatoma cells

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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