The anticancer properties and apoptosis-inducing mechanisms of cinnamaldehyde and the herbal prescription Huang-Lian-Jie-Du-Tang (Huáng Lián Jiě Dú Tang) in human hepatoma cells

Liang Tzung Lin, Shu Jing Wu, Chun Ching Lin

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15 Citations (Scopus)


Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Huáng Lián Jiě Dú Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.

Original languageEnglish
Pages (from-to)227-233
Number of pages7
JournalJournal of Traditional and Complementary Medicine
Issue number4
Publication statusPublished - 2013



  • Anticancer
  • Apoptosis
  • Cinnamaldehyde
  • Hepatoma
  • Huang-Lian-Jie-Du-Tang

ASJC Scopus subject areas

  • Complementary and alternative medicine

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