Testicular mixed germ cell tumor presenting with seizure as the initial symptom: A case report and literature review

Research output: Contribution to journalArticlepeer-review

Abstract

Most patients with testicular germ cell tumor present with a painless scrotal mass. We report a 19-year-old patient who presented with neurological complains. Rapid clinical progression to coma was noted during the staging work up. A diagnosis of testicular mixed germ cell tumor with multiorgan metastasis (lymph node, lung, liver and brain) was made. Patients with brain metastasis should receive chemotherapy alone or combined with surgery or radiotherapy. Because the clinical symptoms deteriorated quickly, surgery was used upfront followed by chemotherapy and radiotherapy for the brain tumor. After the first stage of treatment, the clinical symptoms, tumor markers and imaging findings were improved. The residual brain tumor was eliminated by chemotherapy, and only sparse degenerated tumor cells were noted in the brain tissue. Longer follow up is required to assess the impact of our treatment strategy.

Original languageEnglish
Pages (from-to)629-633
Number of pages5
JournalInternational Braz J Urol
Volume45
Issue number3
DOIs
Publication statusPublished - May 1 2019

Keywords

  • Neoplasm Metastasis
  • Testicular Germ Cell Tumor 1 [Supplementary Concept]
  • Testis

ASJC Scopus subject areas

  • Urology

Fingerprint Dive into the research topics of 'Testicular mixed germ cell tumor presenting with seizure as the initial symptom: A case report and literature review'. Together they form a unique fingerprint.

Cite this