Taiwanese Version of the M. D. Anderson Symptom Inventory: Symptom Assessment in Cancer Patients

Chia-Chin Lin, Ai Ping Chang, Charles S. Cleeland, Tito R. Mendoza, Xin Shelley Wang

Research output: Contribution to journalArticlepeer-review

66 Citations (Scopus)


The purpose of this study was to validate the Taiwanese version of the M. D. Anderson Symptom Inventory (MDASI-T) in a sample of 556 Taiwanese patients with multiple diagnoses of cancer. The internal consistency Cronbach alpha was 0.89 for symptom severity items and 0.94 for interference items. The test-retest reliability was 0.97 for the severity composite score and 0.96 for the interference composite score over a 3-day interval in a sample of 12 patients. Construct validity was established by factor analysis, which revealed a two-factor structure. Concurrent validity was examined by correlating the MADSI-T scores and scores of the Medical Outcome Study 36-Item Short-Form Health Survey. Known-group validity was established by comparing MDASI-T scores between patients having low functional status and those having high functional status (Karnofsky Performance Status scores ≤50 or >50, respectively) and between inpatients and outpatients. The MDASI-T's sensitivity (its ability to detect small differences in reporting variations) was examined by comparing the MDASI-T composite symptom scores and composite interference scores before, during, and one week after treatment in a sample of 20 breast cancer patients receiving chemotherapy. The MDASI-T is a reliable, valid, and sensitive instrument for measuring the severity and interference with daily life of cancer-related symptoms among Taiwanese cancer patients.

Original languageEnglish
Pages (from-to)180-188
Number of pages9
JournalJournal of Pain and Symptom Management
Issue number2
Publication statusPublished - Feb 2007


  • assessment tool
  • reliability
  • sensitivity
  • symptoms
  • Taiwan
  • validation
  • validity

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Clinical Neurology
  • Neurology
  • Nursing(all)


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