Tacrolimus is widely used as an immunosuppressant after allogeneic organ transplantation. It has rarely been reported to cause peripheral neuropathy in renal transplant patients. We reported a tacrolimus-induced peripheral neurotoxic event on a 46-year-old woman after renal transplantation. She has received renal transplantation and presented asymmetric bilateral lower legs weakness 3 weeks after initiation of tacrolimus. Electrophysiological studies confirmed acute asymmetric demyelinating sensorimotor polyneuropathy with axonal damage. The patient had symptoms resolution after reduction of the tacrolimus dose.
- kidney transplantation
- peripheral neuropathy