Systemic lupus erythematosus presented as extensive longitudinal myelitis

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Abstract

Background: longitudinal myelitis (LM) is defined by the continuous lesion of more than four spinal cord segments. LM is a rare variant of acute transverse myelitis and it frequently presented poor responses to immunomodulatory therapy, which resulted in severe and disabling sequelae. We reported a case of acute longitudinal myelitis involving extensive lesions from cervical spinal cord to conus medullaris caused by newly diagnosed SLE. Case Report: A 39 years old man who was previously healthy presented to our hospital due to acute urinary retention with progressive lower limb weakness for a week. Brisk deep tendon reflexes in upper limbs and decreased reflexes in lower limbs were noted on admission. The pin-prick, vibration, and light touch sensations were decreased in the lower limbs. Spinal MRI sagittal view showed an T2WI bright up mass in the spinal cord below C3/4 level with extension to conus medullaris. He was diagnosed SLE based on ARA criteria. After ruling out mimics including NMO and MS, SLE with LM explained what happened to him . Conclusion: Given the poor prognosis of SLE with LM, which resulted in severe and disabling sequelae. More comprehensive understand of the disease course, real mechanisms and treatment strategy are needed.

Original languageEnglish
Pages (from-to)67-71
Number of pages5
JournalActa Neurologica Taiwanica
Volume22
Issue number2
Publication statusPublished - Jun 2013

Keywords

  • Acute transverse myelitis
  • Longitudinal Myelitis
  • Systemic Lupus Erythematosus

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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